Advertisement

Molecular and General Genetics MGG

, Volume 181, Issue 4, pp 562–563 | Cite as

Cross-sensitivity of certain xeroderma pigmentosum and cockayne syndrome fibroblast strains to both ionizing radiation and ultraviolet light

  • Gerald L. Chan
  • John B. Little
Short Communication

Keywords

Radiation Ultraviolet Light Xeroderma Pigmentosum Cockayne Syndrome Fibroblast Strain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Andrews AL, Barrett SF, Robbins JH (1978) Xeroderma pigmentosum neurological abnormalities correlate with colony-forming ability after ultraviolet radiation. Proc Natl Acad Sci USA 75:1984–1988Google Scholar
  2. Arlett CF, Harcourt SA (1980) Survey of radiasensitivity in a variety of human cell strains. Cancer Res 40:926–932Google Scholar
  3. Arlett CF, Harcourt, SA, Lehmann AR, (1980) Studies on a new case of xeroderma pigmentosum (XP3BR) from complementation group G with cellular sensitivity to ionizing radiation. Carcinogenesis 1:745–751Google Scholar
  4. Cerutti PA (1975) Repairable damage in DNA: Overview. In: Hanawalt PC, Setlow RB (eds) Molecular mechanisms for repair of DNA, Plenum Press, New YorkGoogle Scholar
  5. Chan GL, Little JB (1979) Resistance of plateau phase human normal and xeroderma pigmentosum fibroblasts to the cytotoxic effect of ultraviolet light. Mutation Res 63:401–412Google Scholar
  6. Cox BS, Game J (1974) Repair systems in Saccharomyces. Mutation Res 26:257–264Google Scholar
  7. Hoar DI, Waghorne C (1978) DNA repair in Cockayne syndrome. Am J Hum Genet 30:590–601Google Scholar
  8. Howard-Flanders P., Theriot L, Stedeford JB (1969) Some properties of excision-defective recombination-deficient mutants of Escherichia coli K-12. J Bacteriol 97:1134–1141Google Scholar
  9. Kondo S (1975) DNA repair and evolutionary considerations. Adv Biophys 7:91–162Google Scholar
  10. Lehmann AR, Kirk-Bell S, Arlett CF (1977) Repair of ultraviolet light damage in a variety of human fibroblast cell strains. Cancer Res 37:904–910Google Scholar
  11. Lehmann AR, Kirk-Bell S, Mayne L (1979) Abnormal kinetics of DNA synthesis in ultraviolet light-irradiated cells from patients with Cockayne syndrome. Cancer Res 39:4237–4241Google Scholar
  12. Paterson MC, Smith PJ (1979) Ataxia telangiectasia: An inherited human disorder involving hypersensitivity to ionizing radiation and related DNA-damaging chemicals. Ann Rev Genet 13:291–318Google Scholar
  13. Prakash L, Prakash S (1977) Isolation and characterization of MMS-sensitive mutants of Saccharomyces cerevisiae. Genetics 86:33–55Google Scholar
  14. Regan JD, Setlow RB (1974) Two forms of repair in DNA of human cells damaged by chemical carcinogens and mutagens. Cancer Res 34:3318–3325Google Scholar
  15. Setlow RB, Faulcon FM, Regan JD (1976) Defective repair of gammaray-induced DNA damage in xeroderma pigmentosum cells. Int J Radiat Biol 29:125–136Google Scholar
  16. Wade MH, Chu EHY (1979) Effects of DNA damaging agents on cultured fibroblasts derived from patients with Cockayne syndrome. Mutation Res 59:49–60Google Scholar
  17. Weichselbaum RR, Nove J, Little JB (1980) X-ray sensitivity of fiftythree human diploid fibroblast cell strains from patients with characterized genetic disorders. Cancer Res 40:920–925Google Scholar

Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • Gerald L. Chan
    • 1
  • John B. Little
    • 1
  1. 1.Laboratory of RadiobiologyHarvard University, School of Public HealthBostonUSA

Personalised recommendations