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Memory retrieval deficits: Alleviation by etiracetam, a nootropic drug

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Abstract

Etiracetam, a nonanaleptic drug related to the nootropic substance piracetam, was found to facilitate memory retrieval in rats in several experimental situations, when injected 30 min prior to retention testing. The drug was active when memory deficits were induced by electroconvulsive shock, undertraining, or by a long training-to-test interval. The behavioral paradigms included a one-trial inhibitory avoidance task and a complex multitrial, spatially discriminated approach task. The clinical interest of drugs which facilitate retrieval processes is also discussed.

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Author notes

  1. Susan J. Sara

    Present address: Division of Behavioral Neurology, New York University Medical Center, 341 E. 25th Street, 10010, New York, USA

Authors and Affiliations

  1. Centre de Psychologie Expérimentale et Comparée, University of Louvain, 3041, Pellenberg, Belgium

    Susan J. Sara

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  1. Susan J. Sara
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Additional information

These results were reported, in part, at the Conference on Practical Aspects of Memory, Cardiff, 1978

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Sara, S.J. Memory retrieval deficits: Alleviation by etiracetam, a nootropic drug. Psychopharmacology 68, 235–241 (1980). https://doi.org/10.1007/BF00428109

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  • DOI: https://doi.org/10.1007/BF00428109

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