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Virchows Archiv A

, Volume 375, Issue 2, pp 123–128 | Cite as

Esthesioneuroblastoma

Histological, histochemical and electron microscopic studies of a case
  • Erik Wilander
  • Hans Nordlinder
  • Lars Grimelius
  • Lars -Inge Larsson
  • Clarence Angelborg
Article

Summary

A case of esthesioneuroblastoma was examined by histological, histochemical and electron microscopic techniques. The tumour cells showed an argyrophil reaction with the Grimelius technique and contained cytoplasmic secretory granules, but in contrast to previous reports were devoid of histochemically demonstrable biogenic amines. For routine diagnosis the argyrophil technique may be useful in differentiating this type of tumour from epidermoid carcinoma.

Key words

Esthesioneuroblastoma Light microscopy Electron microscopy Argyrophil reaction Formaldehyde-induced fluorescence 

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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • Erik Wilander
    • 1
    • 2
  • Hans Nordlinder
    • 1
    • 2
  • Lars Grimelius
    • 1
    • 2
  • Lars -Inge Larsson
    • 1
    • 2
  • Clarence Angelborg
    • 1
    • 2
  1. 1.Department of Pathology and Department of OtorhinolaryngologyUniversity of UppsalaUppsalaSweden
  2. 2.Institute of Medical BiochemistryUniversity of AarhusAarhusDenmark

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