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Adrenocortical response to acute and chronic ethanol administration in rats

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Abstract

Acute ethanol administration (2 g/kg IP) induced a significant rise in serum corticosterone levels which seemed to be related to blood ethanol concentration. Chronic ethanol administration, in the form of a liquid diet for 16 or 30 days, did not alter the levels of serum corticosterone. Chronic treatment of rats with a liquid diet containing ethanol resulted in the development of tolerance.

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Guaza, C., Torrellas, A. & Borrell, S. Adrenocortical response to acute and chronic ethanol administration in rats. Psychopharmacology 79, 173–176 (1983). https://doi.org/10.1007/BF00427806

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  • DOI: https://doi.org/10.1007/BF00427806

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