Abstract
The relationship between plasma concentration and effect on arousal was studied in normal subjects after single oral and parenteral doses of melperone. A strong correlation between plasma concentration and effect was found when the effector compartment and central compartment were in equilibrium. The relationship was independent of the route of administration.
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Molander, L., Borgström, L. Relationship between plasma concentration and arousal in normal subjects after single oral and parenteral doses of melperone, a butyrophenone neuroleptic. Psychopharmacology 79, 111–114 (1983). https://doi.org/10.1007/BF00427795
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DOI: https://doi.org/10.1007/BF00427795