Abstract
Normal haloperidol-injected rats were tested on a standard catalepsy bar test, using varying bar heights, diameters, and descent latency measurement criteria. The results demonstrated that all these small procedural differences can markedly influence the duration of catalepsy exhibited by rats and should be standardized in catalepsy experiments.
References
Amir S, Brown ZW, Amit Z, Ornstein K (1981) Body pinch induces long lasting cataleptic like immobility in mice: behavioral characterization and the effect of naloxone. Life Sci 28: 1189–1194
Asin KE, Wirtshafter D, Fibiger HC (1982) Alterations in drug induced catalepsy and post-decapitation convulsions following brain and spinal cord depletion of norepinephrine by the neurotoxin DSP-4. Life Sci 30:1531–1536
Balsara JJ, Jadhav JH, Chandorkar AG (1980) Effect of intraperitoneally administered GABA on haloperidol-induced catalepsy in the rat. Psychopharmacology 68:105–107
Campbell A, Herschel M, Cohen BM, Baldessarini RJ (1980) Tissue levels of haloperidol by radioreceptor assay and behavioral effects of haloperidol in the rat. Life Sci 27:633–640
Costall B, Hui S-CG, Naylor RJ (1978) Correlation between multitest and single test catalepsy assessment. Neuropharmacology 17:761–764
Costall B, Fortune DH, Naykor RJ (1981) Relevance of the rodent area postrema to dopamine-dependent behavioural effects. J Pharm Pharmacol 33:257–259
de Ryck M, Schallert T, Teitelbaum P (1980) Morphine versus haloperidol catalepsy in the rat a behavioral analysis of postural support mechanisms. Brain Res 201:143–172
Fuenmayor LD, Vogt M (1979) Production of catalepsy and depletion of brain monoamines by a butyrophenone derivative. Br J Pharmacol 67:115–122
Kuschinsky K, Hornykiewicz O (1977) Morphine catalepsy in the rat: relation to striatal dopamine metabolism. Eur J Pharmacol 281:167–173
Lloyd KG, Willigens MT, Worms P (1981) Cortical lesions differently affect neuroleptic- and non-neuroleptic induced catalepsy in rats. Br J Pharmacol 54:821P
Moleman P, Versluis DJ, Bruinvels J (1978) Is morphine-induced catalepsy related to activation of dopaminergic neurons? Psychopharmacology 60:35–39
Muller P, Seeman P (1974) Neuroleptics: relation between cataleptic and anti-turning actions, and role of the cholinergic system. J Pharm Pharmacol 26:981–983
Poulos CX, Hinson R (1982) Pavlovian conditional tolerance to haloperidol catalepsy: evidence of dynamic adaptation in the dopaminergic system. Science 218:491–492
Sanberg PR, Pisa M, Faulks IJ, Fibiger HC (1980) Experiential influences on catalepsy. Psychopharmacology 69:225–226
Shipley JE, Rowland N, Antelman SM, Buggy J, Edwards DJ, Shapiro AP (1981) Increased amphetamine stereotypy and longer haloperidol catalepsy in spontaneously hypertensive rats. Life Sci 28:745–753
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sanberg, P.R., Pevsner, J. & Coyle, J.T. Parametric influences on catalepsy. Psychopharmacology 82, 406–408 (1984). https://doi.org/10.1007/BF00427696
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00427696