Skip to main content
Log in

Effects of marihuana use on body weight and caloric intake in humans

  • Human Pharmacology
  • Published:
Psychopharmacology Aims and scope Submit manuscript

Abstract

Body weight and caloric intake were measured in a group of heavy and casual marihuana users prior to, during and following 21 days of marihuana smoking under research ward conditions. A group of control subjects were studied under identical conditions, but they did not smoke marihuana. Both heavy and casual marihuana users had a significant increase in caloric intake and gained weight during the marihuana smoking period. Heavy and casual users gained an average of 3.7 and 2.8 lbs respectively during the first 5 days of marihuana smoking. In contrast, control subjects gained only a small amount of weight (0.2 lbs) during the same time interval. Water retention did not appear to be a major factor in weight gain by the marihuana users. These findings are in agreement with both anecdotal reports and previous experimental data that marihuana use is associated with increased caloric intake and weight gain.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Abel, E. L., Schiff, B. B.: Effects of the marihuana homologue, pyrahexyl, on food and water intake, and curiosity in the rat. Psychon. Sci. 16, 38 (1969)

    Google Scholar 

  • Benowitz, N. L., Jones, R. T.: Cardiovascular effects of prolonged delta-9-tetrahydrocannabionol ingestion. Clin. Pharmacol. Ther. 18, 287–297 (1975)

    Google Scholar 

  • Elsmore, T. F., Fletcher, G. V.: Aversive effects in rat at high doses, Δ 9 tetrahydrocannabinol. Science 175, 911–912 (1972)

    Google Scholar 

  • Gluck, J. P., Ferraro, D. P.: Effects of Δ 9 THC on food and water intake of deprivation experienced rats. Behav. Biol. 11, 395–401 (1974)

    Google Scholar 

  • Haines, L., Green, W.: Marijuana use patterns. Brit. J. Addict. 65, 347–362 (1970)

    Google Scholar 

  • Hollister, L. E.: Hunger and appetite after single doses of marihuana, alcohol, dextroamphetamine. Clin. Pharmacol. Ther. 12, 44–49 (1971)

    Google Scholar 

  • Manning, F. J., McDonough, J. H., Jr., Elsmore, T. F., Saller, C., Sodetz, F. J.: Inhibition of normal growth by chronic administration of delta-9 tetrahydrocannabinol. Science 174, 424–426 (1971)

    Google Scholar 

  • Mendelson, J. H., Meyer, R. E., Rossi, A. M., Bernstein, J. G., Patch, V. D., Babor, T. F., Reed, H., Salzman, C., Becker, D.: In: Marihuana: A signal of misunderstanding, Technical Papers 1, 68, U.S. Government Printing Office (1972)

  • Mendelson, J. H., Kuehnle, J. C., Ellingboe, J., Babor, T. F.: Plasma testosterone levels before, during and after chronic marihuana smoking. New Engl. J. Med. 291, 1051–1055 (1974)

    Google Scholar 

  • Regelson, W., Butler, J. R., Schultz, J., Kirk, T., Peek, L., Green, M. L.: Delta-9 tetrahydrocannabinol (Delta 9-THC) as an effective antidepressant and appetite-stimulating agent in advanced cancer patients. Paper read at International Conference on the Pharmacology of Cannabis, Savannah, Ga. (1974)

  • Siler, J. F., Sheep, W. L., Bates, L. B., Clark, G. F., Cook, G. W., Smith, W. A.: Marijuana smoking in Panama. Milit. Surg. 269–280 (1933)

  • Sjoden, P., Järbe, T., Henrikksson, B.: Influence of tetrahydrocannabinol (Δ 9-THC and Δ 9-THC) on body weight, food, and water intake in rats. Pharmacol., Biochem. Behav. 1, 395–399 (1973)

    Google Scholar 

  • Snyder, S. H.: Uses of marijuana. New York: Oxford University Press 1971

    Google Scholar 

  • Sofia, R. D., Barry, H.: Acute and chronic effects of Δ 9-Tetrahydrocannabinol on food intake by rats. Psychopharmacologia (Berl.) 39, 213–222 (1974)

    Google Scholar 

  • Williams, E. G., Himmelsbach, C. K., Wikler, A., Ruble, D. C.: Studies on marijuana and pyrahexyl compound. Publ. Hlth. Rep. (Wash.) 61, 1059–1083 (1946)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Greenberg, I., Kuehnle, J., Mendelson, J.H. et al. Effects of marihuana use on body weight and caloric intake in humans. Psychopharmacology 49, 79–84 (1976). https://doi.org/10.1007/BF00427475

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00427475

Key words

Navigation