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Effect of caffeine on the memory of the mouse

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Abstract

Albino mice were injected i.p. with caffeine (27.9 mg/kg) 10 min pre-trial. The mice had no trial retention (300-s period) after 24h. This result suggests that caffeine, at this dose, would upsets some mechanism involved in memory processes.

No correlation is observed between serotonin (5-HT) increase and caffeine's effect on retention.

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Authors and Affiliations

  1. Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Consejo Nacional de Investigaciones Cientificas y Técnicas (CONICET), Obligado 2490, 1428, Buenos Aires, Aregentina

    Juan A. Izquierdo, Stella Maris Costas, Eduardo Adolfo Justel & Graciela Rabiller

Authors
  1. Juan A. Izquierdo
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  2. Stella Maris Costas
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  3. Eduardo Adolfo Justel
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  4. Graciela Rabiller
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Additional information

Career Investigator of National Research Council of Argentina (CONICET)

Fellowship of National Research Council of Argentina (CONICET)

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Izquierdo, J.A., Costas, S.M., Adolfo Justel, E. et al. Effect of caffeine on the memory of the mouse. Psychopharmacology 61, 29–30 (1979). https://doi.org/10.1007/BF00426806

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  • DOI: https://doi.org/10.1007/BF00426806

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