Psychopharmacology

, Volume 53, Issue 2, pp 165–167 | Cite as

Readaptation time after photo stress

Alcohol-induced acute and post-alcohol ‘hangover’ changes in ocular readaptation time
  • B. Högman
  • H. Bergman
  • S. Borg
  • T. Eriksson
  • L. Goldberg
  • A. W. Jones
  • C.-J. Linde
  • B. Tengroth
Original Investigations

Abstract

The effect of alcohol intake on readaptation time (RAT) after phto stress is studied. Ten healthy subjects were given 0.72 g alcohol per kg body weight to be consumed within 20 min. The tests were made during a total period of 11–12 h. The findings demonstrate that moderate blood alcohol concentrations induce definite changes in RAT. An average RAT-prolongation of 60–70% was seen during the acute phase of intoxication. RAT-prolongation ended before the blood alcohol concentration had reached zero, but did not have the same downward slope. Following a period of reduction, a new prolongation of RAT was observed. The lack of congruence between the RAT-curve and the blood alcohol curve in the acute phase of intoxication and the post-alcohol increase are discussed. It is concluded that the alcoholinduced RAT-changes probably are CNS-effects and that the equipment used constitutes a sensitive method of estimating these effects.

Key words

Alcohol intoxication Nystagmus Central nervous system 

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Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • B. Högman
    • 1
    • 2
    • 3
    • 4
  • H. Bergman
    • 1
    • 2
    • 3
    • 4
  • S. Borg
    • 1
    • 2
    • 3
    • 4
  • T. Eriksson
    • 1
    • 2
    • 3
    • 4
  • L. Goldberg
    • 1
    • 2
    • 3
    • 4
  • A. W. Jones
    • 1
    • 2
    • 3
    • 4
  • C.-J. Linde
    • 1
    • 2
    • 3
    • 4
  • B. Tengroth
    • 1
    • 2
    • 3
    • 4
  1. 1.Department of Ophthalmology at the Karolinska HospitalKarolinska InstituteStockholmSweden
  2. 2.Department of Clinical Alcohol and Drug Research at the Karolinska HospitalStockholmSweden
  3. 3.Department of Psychiatry at St. Göran's HospitalStockholmSweden
  4. 4.Department of Alcohol ResearchStockholmSweden

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