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Effects of diazepam on operant behavior in man

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Abstract

The effects of diazepam (10 mg orally) on the responding of normal human volunteers was studied in a procedure that involved the maintenance of operant behavior by monetary reinforcement and its suppression by monetary loss (punishment). Diazepam produced an antipunishment effect as shown by an increase in behavior suppressed by monetary loss. An analogy to animal procedures that selectively detect antianxiety drugs is apparent.

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Carlton, P.L., Siegel, J.L., Murphree, H.B. et al. Effects of diazepam on operant behavior in man. Psychopharmacology 73, 314–317 (1981). https://doi.org/10.1007/BF00426457

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  • DOI: https://doi.org/10.1007/BF00426457

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