Skip to main content
SpringerLink
Log in

Induction of damage inducible (SOS) repair in dam mutants of Escherichia coli exposed to 2-aminopurine

  • Short Communication
  • Published:
Molecular and General Genetics MGG Aims and scope Submit manuscript

Summary

2-Aminopurine induces damage inducible (SOS) repair in an Escherichia coli dam-4 strain but not in a dam-4 mutS456 derivative or in dam + bacteria.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Glickman BW, Radman M (1980) Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction. Proc Natl Acad Sci USA 77:1063–1067

    Google Scholar 

  • Glickman BW, van den Elsen P, Radman M (1978) Induced mutagenesis in dam - mutants of Escherichia coli, a role of 6-methyladenine residues in mutation avoidance. Mol Gen Genet 163:307–312

    Google Scholar 

  • Herman GE, Modrich P (1981) Escherichia coli K-12 clones that overproduce dam methylase are hypermutable. J Bacteriol 145:644–646

    Google Scholar 

  • Kenyon CJ, Walker GC (1980) DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. Proc Natl Acad Sci USA 77:2819–2823

    Google Scholar 

  • Little JW Mount DW (1982) The SOS regulatory system of Escherichia coli. Cell 29:11–22

    Google Scholar 

  • Marinus MG (1984) Methylation of procaryotic DNA. In: Razin A, Cedar H, Riggs A (eds) DNA methylation. Springer Verlag, New York, in press

    Google Scholar 

  • McGraw BR, Marinus MG (1980) Isolation and characterization of Dam + revertants and suppressor mutations that modify secondary phenotypes of dam-3 strains of Escherichia coli K-12. Mol Gen Genet 178:309–315

    Google Scholar 

  • Miller JH (1972) Experiments in molecular genetics. Cold Spring Harbor Laboratory, New York, p 466

    Google Scholar 

  • Pukkila P, Peterson J, Herman G, Modrich P, Meselson M (1983) Effects of high levels of DNA adenine methylation on methyl directed mismatch repair in E. coli Genetics 104:571–582

    Google Scholar 

  • Rydberg B (1978) Bromouracil mutagenesis and mismatch repair in mutator strains of Escherichia coli. Mutat Res 52:11–24

    Google Scholar 

  • Wagner RW, Meselson M (1976) Repair tracts in mismatched DNA heteroduplexes. Proc Natl Acad Sci USA 73:4135–4139

    Google Scholar 

Download references

Author information

Author notes

  1. Robert J. Craig

    Present address: Biogen, 241 Binney St., 02142, Cambridge, MA, USA

Authors and Affiliations

  1. Department of Pharmacology, University of Massachusetts Medical School, 55 Lake Avenue North, 01605, Worcester, MA, USA

    Robert J. Craig, Judy A. Arraj & M. G. Marinus

Authors
  1. Robert J. Craig
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Judy A. Arraj
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. G. Marinus
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Communicated by P.T. Emmerson

Rights and permissions

Reprints and permissions

About this article

Cite this article

Craig, R.J., Arraj, J.A. & Marinus, M.G. Induction of damage inducible (SOS) repair in dam mutants of Escherichia coli exposed to 2-aminopurine. Molec. Gen. Genet. 194, 539–540 (1984). https://doi.org/10.1007/BF00425572

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00425572

Keywords

Search

Navigation