Summary
Using a set of overlapping deletion mutants in the tetracycline-resistance transposon Tn10, it has been established that certain regions of the Tn10 genome exert a powerful inhibition on translocation of an intact Tn10 element into the bacterial genome. Such inhibition is strongly temperature dependent: at 37° C translocation is inhibited by at least a factor of 100; no inhibition of translocation is detected at 30° C.
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Communicated by M.M. Green
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Beck, C.F., Moyed, H. & Ingraham, J.L. The tetracycline-resistance transposon Tn10 inhibits translocation of Tn10. Molec. Gen. Genet. 179, 453–455 (1980). https://doi.org/10.1007/BF00425476
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DOI: https://doi.org/10.1007/BF00425476