Abstract
The weights of testes, prostates, adrenals, thymus and the pituitary of rats with apomorphine induced aggressiveness did not differ from those without aggressiveness. Postpubertal castration, adrenalectomy or thyroidectomy did not reduce the apomorphine induced aggressive behaviour, but a considerable reduction was found after hypophysectomy.
Prepubertal castration significantly reduced, but did not completely abolish the proportion of aggressive rats, especially when castration was performed on the 5th day.
Prolonged treatment of male, female and castrated rats with high doses of testosterone from the time of weaning increased the proportion of aggressive animals. Less intensive treatment and treatment of adult rats were ineffective.
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Une communication portant sur une partie de ces résultats a été présentée au 4ème Congrès International de Pharmacologie — Bâle 14–18 juillet 1969 (Senault, 1969).
L'auteur remercie vivement le Docteur J. Jacob pour les conseils qu'il lui a apportés au cours de ce travail et de la rédaction de ce manuscrit. Il remercie également Madame Erba et Monsieur J. Cheret pour leur précieuse aide technique.
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Senault, B. Influence de la surrénalectomie, de l'hypophysectomie, de la thyroidectomie, de la castration ainsi que de la testostérone sur le comportement d'agressivité intraspécifique induit par l'apomorphine chez le rat. Psychopharmacologia 24, 476–484 (1972). https://doi.org/10.1007/BF00423438
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DOI: https://doi.org/10.1007/BF00423438