Antagonistic effects of endurance training and testosterone on alkaline proteolytic activity in rat skeletal muscles

  • B. Dahlmann
  • A. Widjaja
  • H. Reinauer


Endurance swimming training for 8 weeks led to an increase by about 50% of alkaline proteinase activity in musculus extensor digitorum longus and about 10% in musculus soleus of normal male rats as compared to sedentary control rats. This exercise-mediated increase of proteolytic activity was prevented by the simultaneous administration of 10 mg testosterone propionate/kg body weight twice a week. The data suggest that testosterone has a regulatory effect on the alteration of the protein-degradative mechanism during endurance training.

Key words

Training Testosterone Muscle alkaline proteinases 


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Copyright information

© Springer-Verlag 1981

Authors and Affiliations

  • B. Dahlmann
    • 1
  • A. Widjaja
    • 1
  • H. Reinauer
    • 1
  1. 1.Biochemische AbteilungDiabetes-ForschungsinstitutDüsseldorf 1Federal Republic of Germany

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