Abstract
The effects of anti-agressive agent Sch 12679 were evaluated upon stable baselines of rage and predation elicited by electrical stimulation of the hypothalamus in cats. Sch 12679 depressed approach and terminal aspects of both forms of attack. This is consistent with previous reports, and suggests the drug is effective in reducing many forms of aggression including brain stimulated emotional behavior.
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This research was supported by Grant MH 15946 from the National Institute of Mental Health to the second author. We are grateful to Schering Corporation for the generous donation of Sch 12679.
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Katz, R.J., Thomas, E. Effects of a novel anti-aggressive agent upon two types of brain stimulated emotional behavior. Psychopharmacology 48, 79–82 (1976). https://doi.org/10.1007/BF00423310
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DOI: https://doi.org/10.1007/BF00423310