Summary
The effects of 4–6 h head-out immersion on excretion of vanillylmandelic acid (VMA), blood pressure and plasma volume were estimated in 8 endurance-trained (TR) and 8 untrained (UT) subjects. In the trained only a slight increase of VMA excretion occurred (4 h value: +2.7±10.9 ng/ml GFR), but there was a highly significant increase in the UT (+29.0±17.2 ng/ml GFR). VMA values during control experiments in supine position tended to decrease in both groups.
Systolic and diastolic blood pressure fell by 20 mm Hg after beginning of immersion; in the UT plasma volume was reduced while it remained constant in TR.
The results indicate that orthostatic intolerance (o.i.) after immersion is not effected by decreased sympathetic innervation of vessels; in contrast it seems to be partly compensated for by an elevated sympathetic activity at least in the UT. As a main cause for the post-immersion o.i. one might suggest a decrease in renin activity.
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Supported by the Minister für Wissenschaft und Forschung des Landes Nordrhein-Westfalen, Grant No. 06/0604/685 11
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Skipka, W., Deck, K.A. & Böning, D. Effect of physical fitness on vanillylmandelic acid excretion during immersion. Europ. J. Appl. Physiol. 35, 271–276 (1976). https://doi.org/10.1007/BF00423286
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DOI: https://doi.org/10.1007/BF00423286