, Volume 48, Issue 2, pp 233–234 | Cite as

Haloperidol and light reinforcement in the rat

Animal Studies Short Reports


The effect of the anti-psychotic drug, haloperidol (50 mg/kg), on bar pressing in the rat was investigated in a light-reinforcement situation. Drugged animals responded significantly more for response contingent flickering light (RCF) and less for steady light (RCL) than saline injected animals. The finding is consistent with the possible arousal decreasing action of haloperidol and with the notion of an optimum level of arousal.

Key words

Haloperidol Light reinforcement Arousal 


  1. Janssen, P.: Pharmacologie comparee du haloperidol et du triperidol. Encephale 51, 582–601 (1962)Google Scholar
  2. Leuba, C.: Towards some integration of learning theories: the concept of optimum stimulation. Psychol. Rep. 1, 27–33 (1955)Google Scholar
  3. Lowe, G.: The objective assessment of hallucinogenic drug effects in animals. International Research Communications System (73-12) (1973)Google Scholar
  4. Lowe, G., Williams, d. I.: An arousal model of sensory reinforcement. Bull. Brit. Psychol. Soc. 21, 119 (1968)Google Scholar
  5. Lowe, G., Williams, D. I.: Differential reinforcing effects of steady and flickering light on bar pressing in the rat. Psychon. Sci. 15, 231–232 (1969)Google Scholar
  6. Lowe, G., Williams, D. I.: The effect of LSD-25 on light-reinforcement behaviour in the rat. Psychopharmacologia (Berl.) 27, 255–263 (1972)Google Scholar
  7. Monti, J. M., Hance, A. J.: Effects of haloperidol and trifluperidol on operant behaviour in the rat. Psychopharmacologia (Berl.) 12, 34–43 (1967)Google Scholar
  8. Wells, P. A., Williams, D. I., Lowe, G.: Effects of infantile stimulation on light reinforced behaviour in the rat. Anim. Behav. 19, 115–118 (1971)Google Scholar
  9. Williams, D. I., Lowe, G.: Light reinforcement following preadaptation in the illuminated test apparatus. Psychol. Rep. 22, 532 (1968)Google Scholar

Copyright information

© Springer-Verlag 1976

Authors and Affiliations

  • G. Lowe
    • 1
  1. 1.Department of PsychologyUniversity of HullHullEngland

Personalised recommendations