Summary
The chronic effect of training on intraerythrocyte cationic concentrations and on red cell Na+,K+-ATPase pump activity was studied by comparing well-trained athletes with sedentary subjects at rest. Also the acute effect of a 50-min cross-country run on these erythrocyte measurements was studied in the athletes. At rest the intraerythrocyte potassium concentration was increased (P<0.01) in the athletes compared to that of the control subjects. The intraerythrocyte concentrations of sodium and magnesium and red cell Na+, K+-ATPase pump activity were, however, similar in the trained and the untrained subjects.
As compared with the resting condition, the intraerythrocyte potassium concentration was decreased (P<0.05) after exercise in the athletes, and this was accompanied by a minor increase in the intraerythrocyte sodium concentration. Red cell Na+,K+-ATPase pump activity was slightly increased (P<0.05) after exercise.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Adragna NC, Chang JL, Morey MC, Williams RS (1985) Effect of exercise on cation transport in human red cells. Hypertension 7:132–139
Ahlborg B, Bergström J, Ekelund L-G, Hultman E (1967) Muscle glycogen and muscle electrolytes during prolonged physical exercise. Acta Physiol Scand 70:129–142
Bombardieri E, Battistessa R, Crippa F, Esposito G (1984) The effects of an energy stimulator on blood electrolyte and lactate levels in athletes under training. Acta Vitaminol Enzymol 6:57–61
Böning D, Tibes U, Schweigart U (1976) Red cell hemoglobin and electrolyte concentrations during exercise in trained and untrained subjects. Eur J Appl Physiol 35:243–249
Buono MJ, Faucher PE (1985) Intraerythrocyte and plasma osmolality during graded exercise in humans. J Appl Physiol 58:1069–1072
Cohen NS, Ekholm JE, Luthra MG, Hanahan DJ (1976) Biochemical characterization of density-separated human erythrocytes. Biochim Biophys Acta 419:229–242
Hirche H, Schumacher E, Hagemann H (1980) Extracellular K+ concentration and K+ balance of the gastrocnemius muscle of the dog during exercise. Pflügers Arch 387:231–237
Hnik P, Holas M, Krekule I, Kriz N, Mejsnar J, Smiesko V, Ujec E, Vyskocil F (1976) Work-induced potassium changes in skeletal muscle and effluent venous blood assessed by liquid ion-exchanger microelectrodes. Pflügers Arch 362:85–94
Hultman E (1967) Studies on muscle metabolism of glycogen and active phosphate in man with special reference to exercise and diet. J Clin Lab Invest [Suppl] 19:1–63
Kilburn KH (1966) Muscular origin of elevated plasma potassium during exercise. J Appl Physiol 21:675–678
Korge P, Masso R, Roosson S (1974) The effect of physical conditioning on cardiac response to acute exertion. Can J Physiol Pharmacol 52:745–752
MairbÄurl M, Humpeler E, Schwaberger G, Pessenhofer H (1983) Training-dependent changes of red cell density and erythrocytic oxygen transport. J Appl Physiol 55:1403–1407
Moss RF, Raven PB, Knöchel JP, Peckham JR, Blachley JD (1982) The effect of training on resting muscle membrane potentials. In: Knuttgen HG, Vogel JA, Poortmans J (eds) Biochemistry of exercise, vol 13. Human Kinetics Publishers, Champaign pp 806–811
Muylle E, Van Den Hende C, Nuytten J, Oyaert W, Vlaminck K (1982) Preliminary studies on the relationship of red blood cell potassium concentration and performance. In: Snow D, Persson S, Rose R (eds) Equine Exercise Physiology, Proceedings of the first International Conference. Berlington Press, Josxton-Cambridge, pp 366–370
Reinhart WH, StÄubli M, Straub PW (1983) Impaired red cell filterability with elimination of old red blood cells during a 100-km race. J Appl Physiol 54:827–830
Rosenmund A, Binswanger U, Straub PW (1985) Oxidative injury to erythrocytes, cell rigidity and splenic hemolysis in hemodialyzed uremic patients. Ann Intern Med 82:460–465
Saltin B, SjØgaard G, Gaffney FA, Rowell LB (1981) Potassium, lactate, and water fluxes in human quadriceps muscle during static concentrations. Circ Res. [Suppl] 48:18–24
Sterns RH, Cox M, Feig PU, Singer I (1981) Internal potassium balance and the control of the plasma potassium concentration. Medicine 60:339–353
Tibes U, Hemmer B, Schweigart U, Böning D, Fotescu D (1974) Exercise acidosis as cause of electrolyte changes in femoral venous blood of trained and untrained man. Pflügers Arch 34:145–158
Van Beaumont W, Strand JC, Petrofsky JS, Hipskind SG, Greenleaf JE (1973) Changes in total plasma content of electrolytes and proteins with maximal exercise. J Appl Physiol 34:102–106
Webb SC, Poole-Wilson PA (1985) Skeletal muscle potassium loss during isometric exercise. Clin Sci. [Suppl] 68:51P
Wintrobe MM, Lee GR, Boggs DR, Bithell TC, Foerster J, Athens JW, Lukens JN (1981) The mature erythrocyte. In: Wintrobe MM, Lee GR, Boggs DR, Bithell TC, Foerster J, Athens JW, Lukens JN (eds) Clinical hematology. Lea and Febiger, Philadelphia, pp 75–107
Yoshimura H, Inove T, Yamada T, Shiraki K (1980) Anemia during hard physical training (sports anemia) and its causal mechanism with special reference to protein nutrition. World Rev Nutr Diet 35:1–86
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Hespel, P., Lijnen, P., Fiocchi, R. et al. Erythrocyte cations and Na+,K+-ATPase pump activity in athletes and sedentary subjects. Europ. J. Appl. Physiol. 55, 24–29 (1986). https://doi.org/10.1007/BF00422888
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00422888