Abstract
Chewing gum containing nicotine or placebo was given to smokers attending an anti-smoking clinic. During a one week double-blind study subjects receiving nicotine smoked less and chewed less gum than those receiving placebo. The difference in tobacco consumption between the two treatment groups was most apparent among previous heavy smokers. During a 6 month follow-up phase all subjects were offered nicotine-containing chewing gum; the number of nonsmokers then remained fairly constant in the “initial-nicotine group” while it increased in the “initial-placebo group”.
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Brantmark, B., Ohlin, P. & Westling, H. Nicotine-containing chewing gum as an anti-smoking aid. Psychopharmacologia 31, 191–200 (1973). https://doi.org/10.1007/BF00422509
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DOI: https://doi.org/10.1007/BF00422509