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An ethidium bromide induced mutant of Neurospora crassa defective in mitochondrial DNA

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Summary

Slow growing mutants of Neurospora crassa were obtained by ethidium bromide treatment of the wild type strain. A particular mutant ER-3 showed stopper phenotype accompanied by deficient cytochrome spectra. The mutant showed an altered restriction pattern of the mtDNA which indicated a deletion of 25,000bp. The phenotype of the ethidium bromide induced mutant ER-3 seem to be related to the loss of several essential genes due to a deletion in its mtDNA.

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Author notes

  1. Frank D. Niagro

    Present address: Department of Medical Microbiology, College of Veterinary Medicine, University of Georgia, 30602, Athens, GA, USA

Authors and Affiliations

  1. Department of Biological Sciences, University of South Carolina, 29208, Columbia, SC, USA

    Frank D. Niagro & N. C. Mishra

Authors
  1. Frank D. Niagro
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  2. N. C. Mishra
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Niagro, F.D., Mishra, N.C. An ethidium bromide induced mutant of Neurospora crassa defective in mitochondrial DNA. Curr Genet 16, 303–305 (1989). https://doi.org/10.1007/BF00422117

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  • DOI: https://doi.org/10.1007/BF00422117

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