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A pilot study of mesterolone in impotence

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Abstract

Eighteen “primarily” impotent males untreated for at least 6 months participated in a pilot trial with the synthetic androgen mesterolone. In each subject there was a drug free “run-in” period for 3 weeks, 3 weeks mesterolone (25 mg t. i. d.) and a post drug period of 3 weeks. Throughout, daily self ratings and weekly investigator ratings were made. Although there was a slight trend towards improvement during the mesterolone period, this was not significant statistically.

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Cooper, A.J., Ismail, A.A.A. A pilot study of mesterolone in impotence. Psychopharmacologia 26, 379–386 (1972). https://doi.org/10.1007/BF00421903

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