Summary
In homothallic (h 90) Schizosaccharomyces pombe strains mutants occur which exhibit reduced frequencies of mating-type switching. The colonies of such mutants show a mottled iodine reaction. The underlying mutations map either in a switching signal at matl or in switching (swi) genes which are not linked to the mating-type region. Forty-nine swi mutants were examined. They map in ten different swi genes, swi1 to swi10. Seven swi genes were assigned to chromosomes I and II, respectively. Two classes of swi genes can be distinguished: when plated, class I mutants yield only mottled colonies, whereas class Il mutants yield mottled and iodine-negative colonies (most of the latter are h 1).
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Gutz, H., Schmidt, H. Switching genes in Schizosaccharomyces pombe . Curr Genet 9, 325–331 (1985). https://doi.org/10.1007/BF00421601
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DOI: https://doi.org/10.1007/BF00421601