Abstract
Throughout gestation pregnant Wistar rats consumed a liquid diet containing sustagen and ethanol. Control mothers were fed on lab chow. Subsequently, the offspring of the ethanol-fed mothers displayed significantly greater activity (ambulation and rearing) in an open-field test. Further, pups whose mothers were exposed to ethanol consumed significantly more ethanol in a preference test, compared to control offspring.
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References
Archer, J. E., Blackman, D. E.: Prenatal psychological stress and offspring behavior in rats and mice. Develop. Psychobiol 4, 193–248 (1971)
Auroux, M., Dehaupas, M.: Influence de la nutrition de la mère sur le développment tardif du systeme nerveux central de la progéniture. C.R. Soc. Biol. (Paris) 164, 1432 (1970)
Bond, N. W., di Giusto, E. L.: Changes in open-field behavior following short-term alcohol ingestion by rats. Psychol. Rep. 37, 575–578 (1975)
Branchey, L., Friedhoff, A. J.: The influence of ethanol administered to pregnant rats on tyrosine hydroxylase activity of their offspring. Psychopharmacologia (Berl.) 32, 151–156 (1973)
Cantwell, D. P.: Psychiatric illness in the families of hyperactive children. Arch. gen. Psychiat. 27, 414–417 (1972)
Goodwin, D. W., Schulsinger, F., Hermansen, L., Gaze, S. R., Winokur, G.: Alcoholism and the hyperactive child syndrome. J. nerv. ment. Dis. 160, 349–353 (1975)
Ivinskis, A.: The reliability of behavioural measures obtained in the open-field. Aust. J. Psychol. 20, 173–177 (1968)
Ivinskis, A.: A study of validity of open-field measures. Aust. J. Psychol. 22, 175–182 (1970)
Leavitt, F.: Drugs and behavior. Philadelphia: Saunders 1974
Morrison, J. R., Stewart, M. A.: A family study of the hyperactive child syndrome. Biol. Psychiat. 3, 189–195 (1971)
Morrison, J. R., Stewart, M. A.: The psychiatric status of the legal families of adopted hyperactive children. Arch. gen. Psychiat. 28, 888–891 (1973)
Myers, R. D., Holman, R. B.: A procedure for eliminating position habit in preference-aversion tests for ethanol and other fluids. Psychon. Sci. 6, 235–236 (1966)
Myers, R. D., Veale, W. L.: The determinants of alcohol preference in animals. In: The biology of alcoholism, H. Begleiter and B. Kissin, eds., pp. 131–168. New York: Plenum 1971
Smart, J. L.: Activity and exploratory behaviour of adult offspring of undernourished mother rats. Develop. Psychobiol 7, 315–321 (1974)
Vincent, N. M.: The effects of prenatal alcoholism upon motivation, emotionality and learning. Amer. Psychologist 13, 401 (1958)
Zimmermann, R. R., Geist, C. R., Wise, L. A.: Behavioural development, environmental deprivation, and malnutrition. In: Advances in psychobiology, vol. 2, G. Newton and A. H. Riesen, eds., pp. 133–192. New York: Wiley 1974
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Bond, N.W., di Giusto, E.L. Effects of prenatal alcohol consumption on open-field behaviour and alcohol preference in rats. Psychopharmacologia 46, 163–165 (1976). https://doi.org/10.1007/BF00421386
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DOI: https://doi.org/10.1007/BF00421386