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Embryonic and post-natal changes in activity and molecular forms of mucosal cell butyrylcholinesterase in chicken intestine

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Summary

The mucosal cells of the chicken intestine contain a cholinesterase activity essentially due to butyrylcholinesterase. The enzyme is present during embryonic and post-hatching development. The activity reaches a maximum value at day 19 in ovo and decreases prior to and after hatching up to day 4 ex ovo. Then the activity again rises reaching a second maximum at 2–3 weeks. Beyond this stage, the activity slowly decreases leveling off to the value determined in adult chicken. The enzyme exists as two globular forms (G1 and G4) soluble at low-ionic strengths. The G4 form is predominant in ovo up to day 19. From this stage and after hatching the G1 form is the main one. This change in the form proportion differentiates the mucosal cell butyrylcholinesterase from butyrylcholinesterase of other origins such as the chicken plasma enzyme which always shows a predominant G4 form.

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Abbreviations

AChE:

Acetylcholinesterase

BuChE:

Butyrylcholinesterase

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Authors and Affiliations

  1. Laboratoire de Biochimie II, Centre de Recherche de Biologie et Physico-Chimie Cellulaires, France

    Jean-Pierre Sine & Bernard Colas

  2. Laboratoire de Biologie du Développement, Faculté des Sciences, 44072, Nantes - Cédex 03, France

    Raymond Ferrand

Authors
  1. Jean-Pierre Sine
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  2. Raymond Ferrand
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  3. Bernard Colas
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Sine, JP., Ferrand, R. & Colas, B. Embryonic and post-natal changes in activity and molecular forms of mucosal cell butyrylcholinesterase in chicken intestine. Mol Cell Biochem 96, 143–151 (1990). https://doi.org/10.1007/BF00420906

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  • DOI: https://doi.org/10.1007/BF00420906

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