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Human leukocyte and fibroblast interferon in a combination therapy of dendritic keratitis

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Summary

Thirty-eight patients with virologically proven dendritic keratitis were treated using either debridement plus human leukocyte interferon (HLI) or debridement plus human fibroblast interferon (HFI) in a randomized, doubleblind study. We administered one drop of HLI or HFI (1×106 reference units/ml) daily and found no significant difference in the action of either type of interferon.

Zusammenfassung

38 Patienten mit virologisch verifizierter Keratitis dendritica wurden in einer randomisierten Doppelblindstudie entweder mit Abrasio plus Humanleukozyteninterferon (HLI) oder Abrasio plus Humanfibroblasteninterferon (HFI) behandelt. Nur ein Tropfen Interferon (1×106 Einheiten/ml) wurde täglich gegeben. Es fand sich kein signifikanter Unterschied zwischen der Wirkung beider Interferone.

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Authors and Affiliations

  1. Universitätsaugenklinik, Killianstr. 5, D-7800, Freiburg, Federal Republic of Germany

    Rainer Sundmacher & Christoph Hallermann

  2. Central Public Health Laboratory, SF-00280, Helsinki, Finland

    Kari Cantell

  3. Fa. Rentschler, D-7958, Laupheim, Federal Republic of Germany

    Rastislav Skoda

  4. Institut für Virologie im Zentrum für Hygiene der Universität, D-7800, Freiburg, Federal Republic of Germany

    Dieter Neumann-Haefelin

Authors
  1. Rainer Sundmacher
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  2. Kari Cantell
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  3. Rastislav Skoda
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  4. Christoph Hallermann
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  5. Dieter Neumann-Haefelin
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With support from the Deutsche Forschungsgemeinschaft

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Sundmacher, R., Cantell, K., Skoda, R. et al. Human leukocyte and fibroblast interferon in a combination therapy of dendritic keratitis. Albrecht von Graefes Arch. Klin. Ophthalmol. 208, 229–233 (1978). https://doi.org/10.1007/BF00419377

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  • DOI: https://doi.org/10.1007/BF00419377

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