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Reihenuntersuchungen der gonosomalen Chromosomenaberrationen bei männlichen Geisteskranken

Sex chromosome aberration screening among male psychiatric patients

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Summary

The authors report of sex chromosome aberration screenings among the patients of the male psychiatric department, University Medical School, Pécs. 310 patients were investigated. The X-chromatin was detected in buccal smears with thionin-staining and the Y-chromatin in peripheric blood smears with quinacrin-staining by the help of fluorescentoptical technique. Two Klinefelter-patients and one YY-patient were diagnostized. The Klinefelter-patients were psychopaths and mentally subnormal, the YY-patient was a paranoid schizophrenic. The incidence of Klinefelter syndrome is 0. 64%, that of the YY syndrome is 0. 32%. Mental relations of sex chromosome aberrations are discussed in detail.

Zusammenfassung

Die Autoren berichten über Reihenuntersuchungen der gonosomalen Chromosomenaberrationen bei Patienten der männlichen psychiatrischen Abteilung der Neurologisch-Psychiatrischen Universitätsklinik von Pécs. Es wurden insgesamt 310 Patienten untersucht. Das X-Chromatin wurde auf Wangenschleimhautausstrichen mit Thionin-Färbung, das Y-Chromatin auf peripheren Blutausstrichen nach Quinacrin-Färbung fluoreszenzoptisch nachgewiesen. Zwei Klinefelter und ein YY-Patient wurden diagnostiziert. Bei den Klinefelter-Patienten war eine mentale Subnormalität bzw. eine psychopathische Persönlichkeitsstörung nachweisbar, der YY-Syndrom-Patient war ein paranoider Schizophrener. Die Frequenz des Klinefelter-Syndroms ist 0, 64%, die des YY-Syndroms 0, 32 %. Die mentalen Beziehungen der gonosomalen Aberrationen wurden ausführlich erörtert.

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Authors and Affiliations

  1. Neurologisch-Psychiatrische Universitätsklinik, Universität Pécs, Rét utca 2, H-7623, Pécs, Ungarn

    M. Trixler, G. Kosztolányi & K. Méhes

  2. Kinderklinik, Universität Pécs, Rét utca 2, H-7623, Pécs, Ungarn

    M. Trixler, G. Kosztolányi & K. Méhes

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  1. M. Trixler
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  2. G. Kosztolányi
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  3. K. Méhes
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Trixler, M., Kosztolányi, G. & Méhes, K. Reihenuntersuchungen der gonosomalen Chromosomenaberrationen bei männlichen Geisteskranken. Arch. F. Psychiatr. U. Z. Neur. 221, 273–282 (1976). https://doi.org/10.1007/BF00418485

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