Abbreviations
- NO:
-
Nitric oxide
- GSH:
-
reduced glutathione
- MDA:
-
malondialdehyde
- MLF:
-
membrane lipid fluidity
- MPM:
-
membrane protein mobility
- NEFA:
-
non-esterified fatty acids
- GSSG:
-
oxidised glutathione
References
Cross CE, Halliwell B, Borish ET et al. (1987) Oxygen radicals and human disease. Ann Intern Med 107: 526–545
Baynes JW (1991) Role of oxidative stress in the development of complications in diabetes mellitus. Diabetes 40: 405–412
Cohen RA (1993) Dysfunction of vascular endothelium in diabetes mellitus. Circulation 87 [Suppl V]: 67–76
Ceriello A (1993) Coagulation activation in diabetes mellitus: the role of hyperglycaemia and therapeutic prospects. Diabetologia 36: 1119–1125
HÄring HU, Mehnert H (1993) Pathogenesis of type 2 (non-insulin-dependent) diabetes mellitus: candidates for a signal transmitter defect causing insulin resistance of the skeletal muscle. Diabetologia 36: 176–182
Hunt JV, Dean RT, Wolff SP (1988) Hydroxyl radical production and autooxidative glycosylation. Glucose autoxidation as the cause of protein damage in the experimental glycation model of diabetes mellitus and ageing. Biochem J 256: 205–212
Brownlee M, Cerami A, Vlassara H (1988) Advanced glycosylation end products in tissue and biochemical basis of diabetic complication. N Engl J Med 318: 1315–1322
Hohman TC, Beg MA (1994) Diabetic complication: progress in the development of treatments. Exp Opin Invest Drugs 3: 1041–1049
Lowenstein CJ, Dinerman JL, Snyder SH (1994) Nitric oxide: a physiologic messenger. Ann Intern Med 120: 227–237
Chari SN, Noth N, Rothi AD (1984) Glutathione and its redox system in diabetic polymorphonuclear leucocytes. Am J Med Sci 287:14–15
DeFronzo RA, Ferrannini E (1991) Insulin resistance: a multifaceted syndrome responsible for NIDDM, obesity, hypertension and atherosclerotic cardiovascular disease. Diabetes Care 14:173–194
Krieger-Brauer H, Kather H (1992) Human fat cells possess a plasma membrane bound H2O2 generating system that is activated by insulin via a mechanism bypassing the receptor kinase. J Clin Invest 89: 1006–1013
Habib MP, Dickerson FD, Mooradian AD (1994) Effect of diabetes, insulin and glucose load on lipid peroxidation in the rat. Metabolism 43:1442–1445
Rowe JW, Young JB, Minaker KL, Stevens AL, Pallotta J, Landsberg L (1981) Effect of insulin and glucose infusion on sympathetic nervous system activity in normal men. Diabetes 30: 219–225
Singal PK, Beamish RE, Dhalla NS (1983) Potential oxidative pathways of catecholamines in the formation of lipid peroxides and genesis of heart disease. Adv Exp Med Biol 161: 391–401
RÄndle PJ, Priestman DA, Mistry S, Halsall A (1994) Mechanisms modifying glucose oxidation in diabetes mellitus. Diabetologia 37[Suppl 2]: S155-S161
Toborek M, Henning B (1994) Fatty acid-mediated effects on the glutathione redox cycle in cultured endothelial cells. Am J Clin Nutr 59: 60–65
Henning B, Enoch C, Chow CK (1983) Protection by vitamin E against endothelial cell injury by linoleic acid hydroperoxides. Nutr Res 7: 1253–1259
Tamura H, Shibamoto T (1991) Gas chromatographic analysis of malon-aldehyde and 4-hydroxy-2-(E)-noneal- produced from arachidonic acid and linoleic acid in a lipid peroxidation model system. Lipids 26: 170–173
Toborek M, Henning B (1992) Effect of different fatty acids on ATP levels in cultured endothelial cells. FASEB 6: 1322A (Abstract)
Hiramatsu K, Arimori S (1988) Increased superoxide production by mononuclear cells of patients with hypertriglyceridemia and diabetes. Diabetes 37: 832–837
Dianzani MU (1990) Free radicals and aging. In: Fabris F, Pernigotti L, Ferrario E (eds) Sedentary life and nutrition. Raven Press, New York pp 27–37
Caimi G, Serra A, Lo Presti R, Sarno A (1992) Red cell membrane protein lateral mobility in diabetes mellitus. Horm Metab Res 24: 409–411
Jain SK, McVie R (1994) Effect of glycemic control, race (white versus black) and duration of diabetes and reduced glutathione content in erythrocytes of diabetic patients. Metabolism 43: 306–309
Whitesell RR, Regen DM, Beth AH, Pelletier DK, Abumrad NA (1989) Activation energy of the slowest step in the glucose carrier cycle: correlation with membrane lipid fluidity. Biochemistry 28: 5618–5625
Paolisso G, Di Maro G, Pizza G et al. (1992) Plasma GSH/GSSG affects glucose homeostasis in healthy subjects and non-insulin dependent diabetics. Am J Physiol 263: E435-E440
Paolisso G, D'Amore A, Volpe C et al. (1994) Evidence for a relationship between oxidative stress and insulin action in non-insulin dependent (type II) diabetic patients. Metabolism 43: 1426–1429
Lewis RE, Czech MP (1987) Phospholipid environment alters hormone sensitivity of the purified insulin receptor kinase. Biochem J 248: 829–836
Tong P, Thomas T, Berrish T et al. (1995) Cell membrane dynamics and insulin resistance in non-insulin dependent diabetes mellitus. Lancet 345: 357–358
Devynck MA (1995) Do cell membrane dynamics participate in insulin resistance? Lancet 345: 336–337
Borkman M, Storlien LH, Pan DD, Jenkins AB, Chisholm DJ, Campbel LV (1993) The relationship between insulin sensitivity and the fatty-acid composition of skeletal muscle phospholipids. N Engl J Med 328: 238–244
Cerrutti PA, Trump B (1991) Inflammation and oxidative stress in carcinogenesis. Cancer Cells 3: 1–7
Geeraerts MD, Ronveaux-Dupal MF, Lemaster JJ, Herman B (1991) Cytosolic free Ca2+ and proteolysis in lethal oxidative injury in endothelial cells. Am J Physiol 261: C889-C896
Levy J, Gavin JR III, Sowers JR (1994) Diabetes mellitus: a disease of abnormal cellular calcium metabolism? Ann Intern Med 96: 260–273
Clausen T, Elrink J, Morten BR (1974) Insulin controlling calcium distribution in muscle and fat cells. Acta Endocrinologica 77: 137–143
Kissebah HA, Hope-Gill H, Vydelinijum N et al. (1974) Mode of insulin action. Lancet i: 144–147
Klip A (1984) Is intracellular Ca involved in insulin stimulation of sugar transport? Fact and prejudice. Can J Biochem 62:1228–1236
Klip A, Li G, Wagon WJ (1984) Role of calcium ions in insulin action and hexose transport in L6 muscle cells. Am J Physiol 247: E297-E304
McDonald JM, Pershadsingh HA (1985) The role of calcium in the transduction of insulin action. In: Czech M (ed) Molecular basis of insulin action. Plenum Publishing, New York pp 103–117
Draznin B, Sussman KE, Kao M et al. (1987) The existence of a optimal range of cytosolic free calcium for insulin-stimulated glucose transport in rat adipocytes. J Biol Chem 262: 14385–14388
Draznin B, Sussman KE, Eckel RH et al. (1988) Possible role of cytosolic free calcium concentration in mediating insulin resistance of obesity and hyperinsulinemia. J Clin Invest 82: 1848–1852
Paolisso G, Gambardella A, Balbi V et al. (1993) Effects of magnesium and nifedipine infusions on insulin action, substrate oxidation and blood pressure in aged hypertensive patients. Am J Hyperten 6: 920–926
Laasko M, Edelman V, Brechtel G, Baron A (1990) Decreased effect of insulin to stimulate skeletal muscle blood flow in obese men. A novel mechanism for insulin resistance. J Clin Invest 85: 1844–1852
Steinberg HO, Brechtel G, Johnson A, Fineberg N, Baron AD (1994) Insulin mediated skeletal muscle vasodilation is nitric oxide dependent. A novel action of insulin to increase nitric oxide release. J Clin Invest 94: 1172–1179
Ganrot PO (1993) Insulin resistance syndrome: possible key role of blood flow in resting muscle. Diabetologia 36: 876–879
Paolisso G, D'Amore A, Balbi V et al. (1994) Plasma vitamin C affects glucose homeostasis in healthy subjects and non-insulin dependent diabetics. Am J Physiol 266: E261-E268
Paolisso G, D'Amore A, Galzerano D et al. (1993) Daily vitamin E supplements improve metabolic control but not insulin secretion in elderly type II diabetic patients. Diabetes Care 16: 1433–1438
Paolisso G, D'Amore A, Giugliano D et al. (1993) Pharmacological doses of vitamin E improve insulin action in healthy subjects and non-insulin dependent diabetic patients. Am J Clin Nutr 57: 650–656
Paolisso G, Di Maro G, Galzerano D et al. (1994) Pharmacological doses of vitamin E and insulin action in elderly subjects. Am J Clin Nutr 59: 1291–1296
Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J (1994) Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. N Engl J Med 331: 1188–1193
Fujiwara T, Yoshioka S, Yoshinka T (1988) Characterization of new oral antidiabetic agent CS-045. Studies in KK and mice a Zucker fatty rats. Diabetes 37: 1549–1558
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Paolisso, G., Giugliano, D. Oxidative stress and insulin action: is there a relationship?. Diabetologia 39, 357–363 (1996). https://doi.org/10.1007/BF00418354
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DOI: https://doi.org/10.1007/BF00418354