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Responses of plasma human atrial natriuretic factor to high intensity submaximal exercise in the heat

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Summary

No data exists regarding responses of human atrial natriuretic factor (ANF) to exercise in the heat. The purpose of this study was to examine the responses of plasma ANF to high intensity submaximal (71%±0.9 \(\dot V_{{\text{O}}_{{\text{2 max}}} } \)) exercise in the heat over an eight day acclimation period. Fourteen healthy males volunteered to participate in the study. Subjects performed intermittent exercises on a treadmill (0% grade) during 50 min of each 100 min trial in an environmental chamber maintained at 41.2±0.5° C, 39.0±1.7% relative humidity. Blood was obtained from an antecubital vein after standing 20 min in the heat prior to exercise, and immediately after exercise. Measures were compared on days 1, 4 and 8. ANF did not change pre- to post-exercise nor did it change over the eight day heat acclimation period despite other heat acclimation adaptations. Conversely, plasma aldosterone (ALDO), renin activity (PRA) and cortisol (COR) all increased (p<0.05) pre- to post-exercise on each day but again no changes were observed over the eight day period. These data support that ANF may not increase when ALDO and PRA increases are observed.

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Human subjects participated in these studies after giving their free and informed voluntary consent. Investigators adhered to AR 70-25 and USAMRDC Regulation 70-25 on Use of Volunteers in Research. The views, opinions, and/or findings contained in this report are those of the author(s) and should not be construed as an official Department of the Army position, policy, or decision, unless so designated by other official documentation

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Kraemer, W.J., Armstrong, L.E., Hubbard, R.W. et al. Responses of plasma human atrial natriuretic factor to high intensity submaximal exercise in the heat. Europ. J. Appl. Physiol. 57, 399–403 (1988). https://doi.org/10.1007/BF00417983

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  • DOI: https://doi.org/10.1007/BF00417983

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