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Capillar- und Mikroaneurysmenverfettung bei diabolischer Retinopathie

Fatty degeneration of capillaries and microaneurysms in diabetic retinopathy

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Summary

The fatty degeneration in 1 000 microaneurysms isolated by the trypsin digestion technique was histologically determined in 40 diabetic retinae.

The quantity of lipid was compared with the size of the microaneurysms, and the local distribution of the fatty aneurysms compared with the presence of fatty capillaries.

The results do not support the hypothesis that a lipid deposition and degeneration of capillaries causes microaneurysms. The pathogenesis of this fatty change is discussed.

Zusammenfassung

An den mit Trypsin isolierten Gefäßen von 40 diabetischen Netzhäuten wurde histologisch die Verfettung von 1000 Mikroaneurysmen bestimmt, in Relation zur Aneurysmengröße gesetzt und mit der Verfettung von Capillaren topisch korreliert. Die Befunde wurden mit den auf gleiche Weise gewonnenen in Netzhäuten mit Zentralvenenthrombose verglichen. Die Resultate sprechen gegen die Hypothese einer für die Entstehung von Mikroaneurysmen kausalen Capillarverfettung. Die Pathogenese der Fettimbibition von Netzhautcapillaren und Mikroaneurysmen wird diskutiert.

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  1. Universitäts-Augenklinik Basel, Schweiz

    B. Daicker

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Daicker, B. Capillar- und Mikroaneurysmenverfettung bei diabolischer Retinopathie. Albrecht von Graefes Arch. Klin. Ophthalmol. 189, 137–145 (1973). https://doi.org/10.1007/BF00417747

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