Skip to main content

Advertisement

Log in

Zusammenfassung

Die Arbeit befaßt sich mit der Beschreibung der Komponenten des Komplexes des posttraumatischen Syndromes. Das pathologische Geschehen der Fettmakroglobulinämie wird eine klinische Einheit, durch Verstopfung der arteriolaren Endungen der vitalen Organe, was die Form des fettembolischen Syndromes erzeugt. Das Hauptproblem in der Physiopathologie, die Lungeninsuffizienz, die sich zu einer akuten oder subakuten Form entwickelt, ist beschrieben. Ebenfalls ist die cerebrale Embolie beschrieben. Die Symptomatologie ist verschieden und nicht charakteristisch, nach der Wichtigkeit der Symptome und Anzeichen als Minder- oder Hauptsymptome wurde sie in der Diagnose der Fettembolie aufgeteilt. Nur in der letzten Zeit ist die Behandlung der Patienten mit fettembolischem Syndrom bekannt, und sie besteht aus einer allgemeinen suportiven Therapie, Atmungstherapie und anti-inflammatorischen Therapie, hauptsächlich einer Corticoidversorgung.

Summary

This paper describes the components of the post-traumatic syndrome. The pathological state of fat macroglobulinemia by occlusion of arteriolar terminal branches of vital organs causes the fat embolic syndrome. The main physiopathological problem is pulmonary insufficiency in an acute or subacute form. The cerebral embolus is second. The symptomatology varies and is not characteristic. According to their importance they were described as minor or major in the diagnosis of fat emboli. Only recently, treatment for the fat emboli syndrome has been initiated, consisting mainly in supportive measures, respiratory care and anti-inflammatory drugs, mainly cortisone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Adar, R.: Pathogenesis and treatment of fat embolism. Harefuah, Israel med. Ass. J. 83 491 (1972)

    Google Scholar 

  2. Adler, F., Peltier, L. F., Lai, S. P.: Fat embolism, the determination of fat in urine by macroscopic and microscopic method. Surgery 47, 959 (1960)

    Google Scholar 

  3. Aladyemoff, L., Weinberg, H., Alkalai, I.: Fat embolism treatment with lytic cocktail and surface cooling. Lancet 1963 II, 13

    Google Scholar 

  4. Ashbaugh, D. G., Petty, T. L.: The use of corticosteroids in the treatment of respiratory failure associated with massive fat embolism. Surg. Gynec. Obstet. 123, 493 (1966)

    Google Scholar 

  5. Benoit, P. R., Hampson, L. G., Burgess, J. H.: Value of arterial hypoxemia in the diagnosis of fat embolism. Ann. Surg. 175, 128 (1972)

    Google Scholar 

  6. Benoit, P. R., Hampson, L. G., Burgess, J. H.: Respiratory gas exchange following fractures. Surg. Forum 208, 214 (1969)

    Google Scholar 

  7. Collins, J. A., Gordon, W. C., Hudson, T. L., Irvin, R. W.: Inapparent hypoxemia in casualties with wounded limbs: pulmonary fat embolism? Ann. Surg. 167, 511 (1968)

    Google Scholar 

  8. Dines, K. K., Lindscheid, H. L., Didier, E. P.: Fat embolism syndrome. Mayo Clin. Proc. 47, 237 (1972)

    Google Scholar 

  9. Gurd, A. R.: Fat embolism: an aid to diagnosis. J. Bone Jt Surg. 52-B, 732 (1970)

    Google Scholar 

  10. McTaggart, D. M., Neubuerger, K. T.: Cerebral fat embolism. Acta neuropath. (Berl.) 15, 183 (1970)

    Google Scholar 

  11. Moore, F. D., Lyons, L. H., Pierce, L. C.: Post-traumatic pulmonary insufficiency. Philadelphia: W. B. Saunders 1969

    Google Scholar 

  12. New aspects of trasylol therapy, Vol. 4. Stuttgart-New York: F. K. Schattauer 1971

  13. Peltier, L. F.: Fat embolism: A current concept. Clin. Orthop. 66, 241 (1969)

    Google Scholar 

  14. Peltier, L. F.: Fat embolism a pulmonary disease. Surgery 62, 756 (1967)

    Google Scholar 

  15. Peltier, L. F.: Fat embolism III. The toxic properties of neutral fat and free fatty acids. Surgery 40, 665 (1956)

    Google Scholar 

  16. Peltier, L. F.: Fat embolism. The detection of fat emboli in the circulating blood. Surgery 36, 198 (1954)

    Google Scholar 

  17. Peltier, L. F., Adler, F., Lai, S. P.: The significance of an elevated serum lipase after trauma to bone. Amer. J. Surg. 99, 821 (1960)

    Google Scholar 

  18. Sevitt, S.: Fat embolism. London: Butterworth's & Co. 1962

    Google Scholar 

  19. Silverstein, A.: The significance of cerebral fat embolism. Neurology 2, 292 (1952)

    Google Scholar 

  20. Tedeschi, C. G., Castelli, V., Kropp, G., Tedeschi, L. G.: Fat macroglobulemia and fat embolism. Surg. Gynec. Obstet. 126, 83 (1968)

    Google Scholar 

  21. Wertzberger, J. J., Peltier, L. F.: Fat embolism: the importance of arterial hypoxia. Surgery 63, 626 (1968)

    Google Scholar 

  22. Wright, B. D.: Fat embolism: Silent respiratory disease. Anaesth. Analg. 49, 279 (1970)

    Google Scholar 

  23. Weisz, G. M., Barzilai, A.: Non-fulminant fat embolism. Anaesth. Analg. 58, 303 (1973)

    Google Scholar 

  24. Weisz, G. M., Steiner, E.: The cause of death in fat embolism. Chest. Dis. Index 59, 511 (1971)

    Google Scholar 

  25. Weisz, G. M., Rang, M., Salter, R. S.: Post-traumatic fat embolism in children. J. Trauma 13, 529 (1973)

    Google Scholar 

  26. Weisz, G. M., Barzilai, A.: New concepts in the fat embolism syndrome. Harefuah, Israel med. Ass. J. 81, 87 (1971)

    Google Scholar 

  27. Weisz, G. M., Schramek, A., Abrahamson, J., Barzilai, A.: Fat embolism in children: Study of its early detection. J. pediat. Surg. 9, 163 (1974)

    Google Scholar 

  28. Weisz, G. M., Fishman, J., Steiner, E.: Callus function in cases of cerebral fat embolism. Confin. neurol. (Basel) 31, 362 (1969)

    Google Scholar 

  29. Weisz, G. M.: Fat embolism. Current problems in surgery. Chicago (Ill.): Year Book Publisher Nov. 1974

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Weisz, G.M., Barzilai, A. Fat embolism: Physiopathology, diagnosis and management. Arch orthop Unfall-Chir 82, 217–223 (1975). https://doi.org/10.1007/BF00417033

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00417033

Keywords

Navigation