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Light-induced skin cancer and prolonged UV-erythema

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Summary

The individual minimal erythema dose (MED) and the persistence of a marked erythema (8 MED) was monitored over 3 weeks (300 nm ± 10 nm) in 4 groups: White students with fair complexion compared with students of homogenous pigmentation as well as skin carcinoma patients compared with a control group of the same age, i.e., older than 50 years.

The MED of the 4 groups gives no significant differences, while the skin carcinoma group shows in 80% a prolonged erythema persistence (control group only 28%). This phenomenon does not seem to correlate with the skin type and may be useful in identifying high-risk patients prone to light-induced skin cancer.

Zusammenfassung

Die individuelle minimale Erythemdosis (MED) und die Persistenz eines deutlichen Erythemes (8 MED) wurde während 3 Wochen (300 nm±10 nm) bei folgenden 4 Gruppen untersucht: Studenten mit heller Komplexion wurden verglichen mit solchen einer homogenen braunen Pigmentierung. Patienten mit Lichtcarcinomen über 50 Jahre alt wurden mit einer Kontrollgruppe verglichen, die keine Carcinome tragen.

Die MED der 4 Gruppen zeigt keine signifikanten Unterschiede. Die Gruppe mit Lichtcarcinomen zeigt in 80% eine überlange Persistenz des Erythems (Kontrollgruppe nur 28%). Dieses Phänomen ist nicht mit dem Hauttyp korreliert und könnte zur prospektiven Identifizierung von Risikopatienten für Lichtcarcinome Anwendung finden.

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Jung, E.G., Furtwängler, M., Klostermann, G. et al. Light-induced skin cancer and prolonged UV-erythema. Arch Dermatol Res 267, 33–36 (1980). https://doi.org/10.1007/BF00416919

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  • DOI: https://doi.org/10.1007/BF00416919

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