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Bioactive compound production by thermophilic and thermotolerant cyanobacteria (blue-green algae)

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Abstract

A thermotolerant species of Phormidium produced extracellular anti-microbial material during batch culture. Although this material was inactive when screened against a number of other cyanobacteria, it inhibited the growth of a wide range of Gram-positive and Gram-negative heterotrophic bacteria, Candida albicans and Cladosporium resinae.

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References

  • Bagchi, S.N., Palod, A. & Chauhan, V.S. 1990 Algicidal properties of a bloom-forming blue-green alga, Oscillatoria sp. Journal of Basic Microbiology 30, 21–29.

    Google Scholar 

  • Bloor, S. & England, R.R. 1989 Antibiotic production by the cyanobacterium Nostoc muscorum. Journal of Applied Phycology 1, 367–372.

    Google Scholar 

  • Brock, T.D. 1978 Thermophilic Microorganisms and Life at High Temperatures. New York: Springer-Verlag.

    Google Scholar 

  • Cannell, R.J.P., Kellam, S.J., Owsianka, A.M. & Walker, J.M. 1987 Microalgae and cyanobacteria as a source of glycosidase inhibitors. Journal of General Microbiology 133, 1701–1705.

    Google Scholar 

  • Cannell, R.J.P., Owsianka, A.M. & Walker, J.M. 1988 Results of a large-scale screening programme to detect antibacterial activity from fresh water algae. British Phycological Journal 23, 41–44.

    Google Scholar 

  • Carmeli, S., Moore, R.E. & Patterson, G.M.L. 1990 Tantazoles: unusual cytotoxic alkaloids from the blue-green alga Scytonema mirabile. Journal of the American Chemical Society 112, 8195–8197.

    Google Scholar 

  • DeCano, M.M.S., DeMulé, M.C.Z., DeCaire, G.Z. & DeHalperin, D.R. 1990 Inhibition of Candida albicans and Staphylococcus aureus by phenolic compounds from the terrestrial cyanobacterium Nostoc muscorum. Journal of Applied Phycology 2, 79–81.

    Google Scholar 

  • DeMulé, M.C.Z., DeCaire, G.Z., DeCano, M.S. & DeHalperin, D.R. 1991 Bioactive compounds from Nostoc muscorum (cyanobacteria). Cytobios 66, 169–172.

    Google Scholar 

  • Drew, S.W. & Demain, A.L. 1977 Effect of primary metabolites on secondary metabolism. Annual Review of Microbiology 31, 343–356.

    Google Scholar 

  • Flint, L.H. & Moreland, C.F. 1946 Antibiosis in the blue-green algae. American Journal of Botany 33, 218.

    Google Scholar 

  • Flores, E. & Wolk, C.P. 1986 Production, by filamentous, nitrogen-fixing cyanobacteria, of a bacteriocin and of other antibiotics that kill related strains. Archives of Microbiology 145, 215–219.

    Google Scholar 

  • Gustafson, K.R., CardellinaII, J.H., Fuller, R.W., Weislow, O.S., Kiser, R.F., Snader, K.M., Patterson, G.M.L. & Boyd, M.R. 1989 AIDS-Antiviral sulfolipids from cyanobacteria (blue-green algae). Journal of the National Cancer Institute 81, 1254–1258.

    Google Scholar 

  • Hanka, L.J., Kuentzel, S.L., Martin, D.G., Wiley, P.F. & Neil, G.L. 1978 Detection and assay of antitumor antibiotics. Recent Results in Cancer Research 63, 69–76.

    Google Scholar 

  • Kashiwagi, S., Mynderse, J.S., Moore, R.E. & Norton, T.R. 1980 Antineoplastic evaluation of Pacific basin marine algae. Journal of Pharmaceutical Sciences 69, 735–738.

    Google Scholar 

  • Kellam, S.J., Cannell, R.J.P., Owsianka, A.M. & Walker, J.M. 1988 Results of a large-scale screening programme to detect antifungal activity from marine and freshwater microalgae in laboratory culture. British Phycological Journal 23, 45–47.

    Google Scholar 

  • Lefèvre, M. 1964 Extracellular products of algae. In Algae and Man, ed Jackson, D.F. pp. 337–367. New York: Plenum.

    Google Scholar 

  • Mason, C.P., Edwards, K.R., Carlson, R.E., Pignatello, J., Gleason, F.K. & Wood, J.M. 1982 Isolation of chlorine containing antibiotic from the freshwater cyanobacterium Scytonema hofmanni. Science 215, 400–402.

    Google Scholar 

  • Mosmann, T. 1983 Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods 65, 55–63.

    Google Scholar 

  • Patterson, G.M.L., Baldwin, C.L., Bolis, C.M., Caplan, F.R., Karnso, H., Larsen, L.K., Levine, I.A., Moore, R.E., Nelson, C.S., Tschappat, K.D., Tuang, G.D., Fursusawa, E., Furusawa, S., Norton, T.R. & Raybourne, R.B. 1991 Antineoplastic activity of cultured blue-green algae (cyanophyta) Journal of Phycology 27, 530–536.

    Google Scholar 

  • Reichelt, J.L. & Borowitzka, M.A. 1984 Antimicrobial activity from marine algae: results of a large scale screening programme. Hydrobiologia 116–117, 158–168.

    Google Scholar 

  • Starr, T.J., Dieg, E.F., Church, K.K. & Allen, M.B. 1962 Antibacterial and antiviral activities of algal extracts studied by acridine orange staining. Texas Reports on Biology and Medicine 20, 271–278.

    Google Scholar 

  • Vaara, T., Vaara, M. & Niemela, S. 1979 Two improved methods for obtaining axenic cultures of cyanobacteria. Applied and Environmental Microbiology 38, 1011–1014.

    Google Scholar 

  • Welch, A.M. 1962 Preliminary survey of fungistatic properties of marine algae. Journal of Bacteriology 83, 97–99.

    Google Scholar 

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The authors are with the Department of Biological Sciences, University of Dundee, Dundee DD1 4HN, UK

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Fish, S.A., Codd, G.A. Bioactive compound production by thermophilic and thermotolerant cyanobacteria (blue-green algae). World Journal of Microbiology & Biotechnology 10, 338–341 (1994). https://doi.org/10.1007/BF00414875

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  • DOI: https://doi.org/10.1007/BF00414875

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