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Elektronenmikroskopische Untersuchungen des Glaskörperskollagens nach Behandeln des Glaskörpers mit verflüssigenden Substanzen

Electron microscopic investigations of vitreous collagen after treating the vitreous with liquefying substances

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Summary

By electron microscopic studies collagenase, hyaluronidase, HCl, ascorbic acid, and iron ions have been found to attack the collagen fibers of bovine vitreous. Because of the possible role of ascorbic acid in collagen synthesis and the ability of ascorbic acid to degrade hyaluronic acid and collagen we suggest that the ascorbic acid of the vitreous essentially participates in construction and metabolism of the vitreous body.

Zusammenfassung

Mit Hilfe elektronenmikroskopischer Studien konnte gezeigt werden daß Kollagenase, Hyaluronidase, HCl, Aseorbinsäure und Eisenionen die Kollagenfibrillen des Rinderglaskörpers angreifen. Da die Ascorbinsäure vermutlich eine Rolle bei der Kollagen-synthese spielt und weil die Ascorbinsäure fähig ist, die Hyaluronsäure und das Kollagen des Glaskörpers anzugreifen, läßt sich vermuten, daß die Ascorbinsäure des Glaskörpers wesentlich am Aufbau und Stoffwechsel des Glaskörpers beteiligt ist.

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  1. Universitäts-Augenklinik Graz, Österreich

    O. Schmut, P. Roll & H. Hofmann

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  1. O. Schmut
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Schmut, O., Roll, P. & Hofmann, H. Elektronenmikroskopische Untersuchungen des Glaskörperskollagens nach Behandeln des Glaskörpers mit verflüssigenden Substanzen. Albrecht von Graefes Arch. Klin. Ophthalmol. 196, 187–197 (1975). https://doi.org/10.1007/BF00414805

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