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Thymoxamine and intraocular pressure

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Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Aims and scope Submit manuscript

Summary

Topical treatment with 1% thymoxamine produces in rabbit and human eyes a small but real miotic and tension-lowering effect.

The latter is more evident using two different models of experimental ocular hypertension in rabbits. In human open-angle glaucoma eyes, tonographic measurements indicate that the outflow facility is left unchanged by the drug.

Zusammenfassung

Die lokale Behandlung mit 1 %igem Thymoxamin führt beim Kaninchen und beim menschlichen Auge zu einer geringen aber eindeutigen Myosis und Drucksenkung.

Die letztere wird deutlicher, wenn man zwei verschiedenartige Modelle von okularer Hypertension beim Kaninchen verwendet. Beim menschlichen Weitwinkelglaucom zeigen tonografische Messungen, daß die “facility of outflow” von dem Medikament nicht beeinflußt wird.

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Authors and Affiliations

  1. University Eye Clinic, Policlinico di Borgo Roma, 1-37100, Verona, Italy

    Luciano Bonomi & Laura Tomazzoli

Authors
  1. Luciano Bonomi
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  2. Laura Tomazzoli
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Bonomi, L., Tomazzoli, L. Thymoxamine and intraocular pressure. Albrecht von Graefes Arch. Klin. Ophthalmol. 204, 95–100 (1977). https://doi.org/10.1007/BF00414710

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  • DOI: https://doi.org/10.1007/BF00414710

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