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Report of a case resembling the ‘fleck retina of Kandori’ with ectodermal peculiarities and macula degeneration


This report involves the case of a 36-year-old woman followed-up for nine years. The symptoms include unique, sharply-defined, irregular, yellow, large flecks of the retina combined with bilateral macula degeneration. The patient's rusty-red hair, enamel dysplasia, and ashen-gray skin color were also noted. It is argued that this case is very likely identical with the ‘fleck retina of Kandori’ and as such, the first case reported outside Japan. The literature is reviewed.


Es wird über eine 36-jährige Frau berichtet, die einzigartige, scharf begrenzte, unregelmäßige, große, gelbe Flecken der Retina sowie eine beidseitige Maculadegeneration aufweist, welche wir über 9 Jahre nachuntersucht haben. Es fanden sich außerdem rostrote Haare, Zahnschmelzdefekte und eine aschgraue Hautfarbe. Sehr wahrscheinlich ist dieser Fall identisch mit der „fleck retina von Kandori” und wäre somit der erste beschriebene Fall dieser Art außerhalb Japans.

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  • Duke-Elder, S.: Textbook of Ophthalmology. Vol. 6, Injuries, London: H. Kimpton, 1954

    Google Scholar 

  • Duke-Elder, S.: Systems of Ophthalmology. Vol. 10, Retina, London: H. Kimpton, 1967

    Google Scholar 

  • Deutman, A.F.: The hereditary dystrophies of the posterior pole of the eye. Assen: Van Gorcum, 1971

    Google Scholar 

  • Deutman, A.F.: Retinal dystrophies with unusually large yellowish flecks. K. Shimizu (Ed.) Int. Congress Series No. 450 XXIII Concilium Ophthalmologicum, Kyoto, 1978, pp. 758–763. Amsterdam-Oxford: Excerpta Medica

    Google Scholar 

  • François, J.: Juvenile macula degenerations. Jp. J. Ophthalmol. 21, 1–21 (1977)

    Google Scholar 

  • Gass, J.D.: Stereoscopic atlas of macular disease. St. Louis: C.V. Mosby, 1970

    Google Scholar 

  • Jaeger, W., Alexandridis, E., Tenner, A., Käfer, O.: Hereditäre Maculadegenerationen. Ber. Dtsch. Ophthatmol. Ges. 73, 695–735 (1973)

    Google Scholar 

  • Kandori, F.: Very rare cases of congenital nonprogressive night blindness with fleck retina. Jp. J. Ophthalmol. 13, 384 (1959)

    Google Scholar 

  • Kandori, R., Setogawa, T., Tamai, A.: Electroretinographical studies on ‘fleck retina’ with congenital nonprogressive night blindness. Yonago Acta Med. 10, 98 (1966)

    Google Scholar 

  • Kandori, F., Tamai, A., Kurimoto, S., Fukunaga, K.: Fleck Retina. Am. J. Ophthalmol. 73, 673–685 (1972)

    Google Scholar 

  • Krill, A.E., Archer, D.B.: Krill's hereditary and choroidal disease. Volume II. Clinical characteristics, pp.: 739–824, 1137–1172. New York, San Francisco, London: Harper & Row, 1977

    Google Scholar 

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Fried, M., Meyer-Schwickerath, G. Report of a case resembling the ‘fleck retina of Kandori’ with ectodermal peculiarities and macula degeneration. Albrecht von Graefes Arch. Klin. Ophthalmol. 211, 307–311 (1979).

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  • Public Health
  • Color
  • Japan
  • Retina
  • Skin Color