Abstract
The continuous retinoblastoma cell line Y79, grown in suspension culture, has been examined by transmission and scanning electron microscopy, including freeze-fracture replica preparations. Four classes of cells were distinguishable by their size and surface characteristics. The surface structures included blebs, filopodia, lamellipodia, microvilli, and microplicae. The possible origin of a most unusual type of cell, apparently forming natural clones, is discussed.
Zusammenfassung
Die kontinuierliche Retinoblastom-Zellinie Y79, die in einer Suspensionskultur gezüchtet wurde, wurde untersucht mit Transmissions- und Rasterelektronenmikroskopie einschließlich Gefrierbruchpräparationen.
4 Klassen von Zellen waren zu unterscheiden aufgrund ihrer Größe und Oberflächenbeschaffenheit. Die Oberflächenstrukturen enthalten Blasen, Filopodien, Lamellipodien, Mikrovilli und Microplicae.
Die mögliche Herkunft eines recht ungewöhnlichen Zelltyps, der offenbar natürliche Klone produziert, wird diskutiert.
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Green, A.L.W., Meek, E.S., White, D.W. et al. Retinoblastoma Y79 cell line: A study of membrane structures. Albrecht von Graefes Arch. Klin. Ophthalmol. 211, 279–287 (1979). https://doi.org/10.1007/BF00414686
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DOI: https://doi.org/10.1007/BF00414686