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Bilateral recurrence of granular corneal dystrophy in the grafts

A clinico-pathologic study

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Summary

Clinical, light- and electron-microscopic findings in two sisters with bilateral recurrence of granular corneal dystrophy in the grafts are presented. The clinical pictures and microscopic findings strongly suggest that granular dystrophy may primarily be an epithelial not a stromal disease.

Zusammenfassung

Bei zwei Schwestern mit typischer bröckliger Hornhautdystrophie entwickelten sich oberflächliche Rezidive auf den Transplantaten nach beidseitiger Keratoplastik. Biopsie- und Abrasionsmaterial von beiden Augen der einen Patientin wurde licht- und elektronenmikroskopisch untersucht. Das klinische und mikroskopische Bild der Rezidive gleicht den Befunden bei frühen Stadien der bröckligen Dystrophie, wie sie in der Literatur mitgeteilt wurden. Es ist anzunehmen, daß es sich bei der bröckligen Dystrophie — ebenso wie bei der verwandten gittrigen Form — um eine primär epitheliale, erst sekundär um eine stromale Erkrankung handelt.

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Authors and Affiliations

  1. University Eye Clinic, Killianstr. 5, D-7800, Freiburg i.Br., Federal Republic of Germany

    H. Witschel & R. Sundmacher

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  1. H. Witschel
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  2. R. Sundmacher
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Witschel, H., Sundmacher, R. Bilateral recurrence of granular corneal dystrophy in the grafts. Albrecht von Graefes Arch. Klin. Ophthalmol. 209, 179–188 (1979). https://doi.org/10.1007/BF00414610

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  • DOI: https://doi.org/10.1007/BF00414610

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