Skip to main content
Log in

Visual evoked potentials as an aid in evaluating brain dysfunction following concussional injury: An animal model

  • Published:
Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Aims and scope Submit manuscript

Abstract

Visual evoked potentials were recorded sequentially, using permanent epidurally implanted electrodes, before and after accelerating the heads of rabbits. The amplitude of VEP, recorded after lesioning, was diminished and recovery time was prolonged depending on the amount of acceleration and the extent of brain lesions found later in histological examinations.

VEP reflected damage to the brain more precisely than EEG or somatosensory evoked potentials, thus giving values for judging the extent of lesions in patients with brain injuries.

Zusammenfassung

Visuell evozierte Potentiale wurden in dichter Folge vor und nach Kopfbeschleunigungen an Kaninchen über dauernd epidural implantierte Elektroden abgeleitet. Die Amplitude des nach der Läsion abgeleiteten VEPs war vermindert und die Erholungszeit verlängert. Beide Schädigungsfolgen waren umso ausgeprägter, je stärker die Beschleunigung und je deutlicher die später histologisch erfaßbaren Hirnveränderungen waren.

In der Erwartung, daß das VEP bei Patienten mit Schädel-Hirnverletzungen wichtige Hinweise auf die Schwere der Verletzung und somit für die Behandlung liefern kann, waren diese Untersuchungen notwendig, um geeignete Untersuchungsmethoden und grundlegende Parameter zu finden.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Denny-Brown D, Russel WR (1941) Experimental cerebral concussion. Brain 64:93–164

    Google Scholar 

  • Feinsod M (1976) Electrophysiological correlates of traumatic visual damage. In: Head injuries, RL McLaurin ed, pp 95–100. Grune and Stratton New York

    Google Scholar 

  • Greenberg RP, Mayer DJ, Becker DP, Miller DJ (1977) Evaluation of brain function in severe human head trauma with multimodality evoked potentials. J Neurosurg 47:150–177

    Google Scholar 

  • Holbourn AHS (1943) Mechanics of head injuries. Lancet II: 438–441

    Google Scholar 

  • Letcher F, Corrao PG, Ommaya AK (1973) Head injury in the chimpanzee. Spontaneous and evoked epidural potentials as indices of injury severity. J Neurosurg 39:167–177

    Google Scholar 

  • Ommaya AK, Gennarelli TA (1974) Cerebral concussion and traumatic unconsciousness. Correlation of experimental and clinical observations on blunt head injuries. Brain 97:633–654

    Google Scholar 

  • Ostertag CB (1979) Über die Entstehung der primären Funktionsstörung und Gewebsschäden nach gedecktem Schädelhirntrauma. Habilitationsschrift Freiburg

  • Röver J, Schaubele G, Berndt K (1980) Macula and periphery: Their contribution to the VEP in humans. Albrecht von Graefes Arch Klin Ophthalmol 214:47–51

    Google Scholar 

  • Singer P, Priquall K (1970) Multiple somatic projections. Exp Neurol 27:438–453

    Google Scholar 

  • Unterharnscheid FJ, Higgins LS (1966) Traumatic lesions of the brain and spinal cord due to nondeforming angular acceleration of the head. Tex Rep Biol Med 27:127–166

    Google Scholar 

  • Wolter I, Noetzel H (1970) Autoradiographische Untersuchungen bei experimenteller Commotio cerebri. Arch Psychiatr Nervenkr 213:46–54

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported by Deutsche Forschungsgemeinschaft SFB 70

Rights and permissions

Reprints and permissions

About this article

Cite this article

Röver, J., Ostertag, C., Schaubele, G. et al. Visual evoked potentials as an aid in evaluating brain dysfunction following concussional injury: An animal model. Albrecht von Graefes Arch. Klin. Ophthalmol. 215, 105–111 (1980). https://doi.org/10.1007/BF00414468

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00414468

Keywords

Navigation