Skip to main content
Log in

Cytochrome P-450-dependent production of chemotactic arachidonate metabolites from human neutrophils

  • Short Communications
  • Published:
Archives of Dermatological Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Bickers DR (1983) Drug, carcinogen and steroid hormone metabolism in the skin. In: Goldsmith LA (ed) Biochemistry and physiology of the skin. Oxford University Press, New York Oxford, pp 1169–1186

    Google Scholar 

  2. Bösterling B, Trudell JR (1983) Leukotriene B4 metabolism by hepatic cytochrome P-450. Biochem Biophys Res Commun 114:850–854

    Google Scholar 

  3. Bösterling B, Trudell JR (1983) Evidence for leukotriene A4 as an intermediate in the conversion of 5-HPETE to leukotriene B4 catalyzed by cytochrome P-450. Biochem Biophys Res Commun 115:995–1001

    Google Scholar 

  4. Capdevila G, Parkhill L, Chacos N, Okita R, Masters BSS, Estabrook RW (1981) The oxidative metabolism of arachidonic acid by purified cytochrome P-450. Biochem Biophys Res Commun 101:1357–1363

    Google Scholar 

  5. Capdevila J, Marnett LJ, Chacos N, Prough RA, Estabrook RW (1982) Cytochrome P-450 dependent oxygenation of arachidonic acid by hydroxyeicosatetraenoic acids. Proc Natl Acad Sci USA 79:767–770

    Google Scholar 

  6. Czarnetzki BM (1983) Release of eosinophil chemotactic leukotrine from, neutrophils of patients with pseudo-allergic reactions. Int Arch Allergy Appl Immunol 70:80–82

    Google Scholar 

  7. Czarnetzki BM, Grabbe J (1983) Biological and chemical characterization of eosinophil chemotactic factors from human leukocytes. Agents Actions [Suppl] 12:204–216

    Google Scholar 

  8. Czarnetzki BM, König W, Lichtenstein LM (1976) Eosinophil chemotactic factor (ECF). 1. Relaase from polymorphonuclear leukocytes by the calcium ionophore A23187. J Immunol 117: 229–234

    Google Scholar 

  9. Czarnetzki BM, Frosch PJ, Mardin M, Macher E (1983) Leukotriene B4 and neutrophil-derived eosinophil chemotactic factor: comparison of their biological activities. Monogr Allergy 18:193–195

    Google Scholar 

  10. Ford-Hutchinson AW, Rackham A, Zambom R, Rokach J, Roy S (1983) Comparative biological activities of synthetic leukotriene B4 and its w-oxidation products. Prostaglandins 25:29–37

    Google Scholar 

  11. Grabbe J, Czarnetzki BM, Mardin M (1982) Chemotactic leukotrienes in psoriasis. Lancet II:1464

    Google Scholar 

  12. Grabbe J, Czarnetzki BM, Mardin M (1984) Release of lipoxygenase products of arachidonic acid from freshly isolated human keratinocytes. Arch Dermatol Res 276:128–130

    Google Scholar 

  13. Grabbe J, Czarnetzki BM, Resenbach, I, Mardin M (1984) Identification of chemotactic lipoxygenase products of arachidonate metabolism in psoriatic skin. J Invest Dermatol (in press)

  14. Netter KJ (1981) Inhibition of oxidative drug metabolism in microsomes. Pharmacol Ther 10:515–535

    Google Scholar 

  15. Oliw EH, Guengerich FP, Oates JA (1982) Oxygenation of arachidonic acid by hepatic monooxygenases. J Biol Chem 257:3771–3781

    Google Scholar 

  16. Ullrich V, Weber P (1972) The O-dealkylation of 7-ethoxycoumarin by liver microsomes. Hoppe-Seyler's Z Physiol Chem 353:1171–1177

    Google Scholar 

  17. Ullrich V, Frommer V, Weber P (1973) Differences in the O-dealcylation of 7-ethoxycoumarin after pretreatment with phenobarbital and 3-methylcholanthrene. Hoppe-Seyler's Z Physiol Chem 354:510–520

    Google Scholar 

  18. Vorhees JJ (1983) Leukotrienes and other lipoxygenase products in the pathogenesis and therapy of psoriasis and other dermatoses. Arch Dermatol 119:541–547

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Czarnetzki, B.M., Goerz, G., Bolsen, K. et al. Cytochrome P-450-dependent production of chemotactic arachidonate metabolites from human neutrophils. Arch Dermatol Res 276, 243–245 (1984). https://doi.org/10.1007/BF00414236

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00414236

Key words

Navigation