Summary
Ten eyes of eight patients with pseudoexfoliation of the lens capsule were first studied by iris fluorescein angiography. Later, iris specimens were obtained at surgery and vessels that were newly formed or showed abnormally rich extravasation of fluorescein were studied electronmicroscopically.
The proliferated vessels had an abnormal basement membrane which was thin or absent, and there was abnormal extracellular material around the vessels. The endothelium was thin and in some cases fenestrae were observed. The electron-microscopic changes agreed with the rich extravasation of fluorescein from the capillaries seen in angiography.
The results show clearly that there are pronounced vascular changes in the anterior part of the eye in pseudoexfoliation. The way in which these changes affect the collection of pseudoexfoliation material in the eye requires further study.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
Literatur
Ashton, N., Shakib, M., Collyer, R., Blach, R.: Electron microscopic study of pseudoexfoliation of the lens capsule. I. Lens capsule and zonular fibers. Invest. Ophthal. 4, 141–153 (1965).
Bill, A.: The protein exchange in the eye with aspects on conventional and uveoscleral bulk drainage of aqueous humours in primates. In: J. W. Rohen (ed.), The structure of the eye. II. Symposium Wiesbaden 1965, p. 313–320. Stuttgart: Schattauer 1965.
Laatikainen, L.: Fluorescein angiographic studies of the peripapillary and perilimbal regions in simple, capsular and low tension glaucoma. Acta ophthal. (Kbh.), Suppl. 111 (1971). M. D. Thesis, Helsinki 1972.
Lindberg, J.: Kliniska undersökningar over depigmentering av pupillarranden och genomlysbarhet av iris vid fall av ålderstarr samt i normala ögon hos gamla personer. M. D. Thesis, Helsingfors 1917.
Okamura, R., Rohen, J. W.: Elektronenmikroskopische Untersuchungen über die Rubeosis iridis. Albrecht v. Graefes Arch. Hin. exp. Ophthal. 182, 53–75 (1971).
Ringvold, A.: Electron microscopy of the wall of iris vessels in eyes with and without exfoliation syndrome (Pseudoexfoliation of the lens capsule). Virchows Arch. Abt. A 348, 328–341 (1969).
Vannas, A.: Fluorescein angiography of the vessels of the iris in pseudoexfoliation of the lens capsule, capsular glaucoma and some other forms of glaucoma. Acta ophthal. (Kbh.), Suppl. 105 (1969).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Vannas, A. Vascular changes in pseudoexfoliation of the lens capsule and capsular glaucoma. Albrecht von Graefes Arch. Klin. Ophthalmol. 184, 248–253 (1972). https://doi.org/10.1007/BF00413298
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00413298