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Brain and heart catecholamine levels after l-Dopa administration in reserpine treated mice: Correlations with a conditioned avoidance response

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Summary

Mice were tested with reserpine before receiving an injection of l-DOPA. At various times after the l-DOPA injection they were sacrificed and the brains and hearts were analyzed for their catecholamine content. Effects on the conditioned avoidance response were further analyzed using reserpine and l-DOPA, and the correlations between the two were discussed.

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Authors and Affiliations

  1. Department of Pharmacology, University of Göteborg, Göteborg, Sweden

    Lewis S. Seiden & Arvid Carlsson

Authors
  1. Lewis S. Seiden
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  2. Arvid Carlsson
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Additional information

United States Public Health Service Postdoctoral Fellow (MPD-10, 562-C 3), National Institute of Mental Health.

This research was supported by the United States Air Force under Grant No. AF-EOAR 63-14 and monitored by the European Office, Office of Aerospace Research (to A. Carlsson).

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Seiden, L.S., Carlsson, A. Brain and heart catecholamine levels after l-Dopa administration in reserpine treated mice: Correlations with a conditioned avoidance response. Psychopharmacologia 5, 178–181 (1964). https://doi.org/10.1007/BF00413240

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  • DOI: https://doi.org/10.1007/BF00413240

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