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Tranquilizer effects on conditioned suppression

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Summary

The effects of chlorpromazine, meprobamate and reserpine on animal experimental conditioned suppression are reported. Over a wide dose range neither chlorpromazine nor meprobamate increased responding for positive reinforcement during a shock-paired stimulus. Reserpine given chronically did increase responding during shock-paired stimuli. The motor depressant effect of reserpine, at suppression attenuating doses, is most probably related to the response measure used since the depressant effects were minimal when discrete trial procedures were studied.

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Authors and Affiliations

  1. Neuropharmacology Research Laboratory, Pittsburgh 6, Pa.

    Oakley S. Ray

  2. Psychology Research Laboratories, Veterans Administration Hospital, Leech Farm Road, 15206, Pittsburgh, Pennsylvania, USA

    Oakley S. Ray

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  1. Oakley S. Ray
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Ray, O.S. Tranquilizer effects on conditioned suppression. Psychopharmacologia 5, 136–146 (1964). https://doi.org/10.1007/BF00413050

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  • DOI: https://doi.org/10.1007/BF00413050

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