Conclusion
Until recently, the effectivity of BP in the treatment of acne vulgaris was considered to be primarily a function of its bacteriostatic action. However, in vitro investigation using pure colonies of P.a. showed that the areas of inhibition produced by a 5% and 10% commercial BP preparation and the isolated vehicle were of about equal size.
This is a preview of subscription content, log in via an institution to check access.
References
Fanta, D., Bardach, H., Jurecka, W.: Klinische Erfahrungen mit Benzoylperoxid in der Behandlung der Acne, vulgaris. Wien. Klin. Wschr. 89, 748–751 (1977)
Fanta, D., Jurecka, W.: Autoradiographic investigations in benzoyl peroxide-treated skin. Acta Dermatol-Venereol. (in press)
Fanta, D., Müller, M. M.: Effect of benzoyl peroxide on skin surface lipids. Dermatologica (in press)
Fulton, J. E., Farzad-Bakshandeh, A., Bradley S.: Studies on the mechanism of action of topical benzoyl peroxide and vitamin A acid in acne vulgaris. J. Cutan. Pathol. 1, 191–200 (1974)
Gloor, M., Hummel, A., Friedrich, H. G.: Experimentelle Untersuchungen zur Benzoylperoxidtherapie der Acne vulgaris. Z. H+G 5, 657–663 (1975)
Huber, C., Christophers, E.: “Keratolytic” effect of salicylic acid. Arch. Dermatol. Res. 257, 293–297 (1977)
Meigel, W. N., Prückner, H.: Therapie der Akne vulgaris mit Panoxyl. Z. Hautkr. 52, 725–732 (1977)
Pace, W. E.: A benzoyl peroxide-sulfur cream for acne vulgaris. Canad. Med. An. J. 93, 252–254 (1965)
Puhvel, S. M., Reisner, R. M.: Effect of antibiotics on the lipases of Corynebacterium acnes in vitro. Arch. Dermatol. 106, 45–49 (1972)
Vasarinsh, D.: Benzoyl-peroxid-sulfur lotion. Arch. Dermatol. 98, 113–186 (1968)
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fanta, D., Bardach, H. & Poitscheck, C. Investigations on the bacteriostatic effect of benzoyl peroxide. Arch Dermatol Res 264, 369–371 (1979). https://doi.org/10.1007/BF00412667
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00412667