Skip to main content
Log in

Fettsäureverteilung der Haarlipide bei der Psoriasis vulgaris

Fatty acid composition of lipids from the hair in psoriasis vulgaris

  • Original Works
  • Published:
Archives of Dermatological Research Aims and scope Submit manuscript

Summary

The composition of fatty acids of hair lipids and the sum of hair and scalp lipids from subjects with Psoriasis vulgaris and a control group was determined by gas liquid chromatography. The analyses indicates that the percentage compositions of lauric acid was distinctly higher by Psoriasis vulgaris.

Zusammenfassung

Bei der gas-chromatographischen Untersuchung der Fettsäureverteilung ds Haarfettes und der gemeinsam analysierten Kopfhaut- und Haarlipide bei einem Kollektiv von Patienten mit Psoriasis vulgaris wurden gegenüber einem Kontrollkollektiv von Hautgesunden eine signifikante Erhöhung der Laurinsäure festgestellt.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literatur

  1. Coon, W. M., Herrmann, F. J., Mandol, L.: Acid number of skin surface lipids in psoriasis. Arch. Dermatol. 83, 619–626 (1961)

    Google Scholar 

  2. Coon, W. M., Wheatley, V. R., Herrmann, F. J., Mandol, L.: Free fatty acids of the skin surface and barrier zone in normal and abnormal keratinization. J. Invest. Dermatol. 41, 259–264 (1963)

    Google Scholar 

  3. Cederkreutz, A.: Über den Fettgehalt der Epidermiszellen bei der Parakeratose. Arch. Dermatol. Syph. (Berl.) 111, 739–742 (1912)

    Google Scholar 

  4. Cornish, H. H., Block, W. D., Lea, W. A.: Distribution of lipids and free amino acids, in psoriatic scale. J. Invest. Dermatol. 32, 43–47 (1959)

    Google Scholar 

  5. Gara, A., Estrada, E., Rothmann, S., Lorincz, A.: Deficient cholesterol esterifying ability of lesion free surfaces in psoriatic individuals. J. Invest. Dermatol. 43, 559–564 (1964)

    Google Scholar 

  6. Gershbein, L., Metcalfe, L.: Gaschromatographic analysis of fatty acids in human hair lipids. J. Invest. Dermatol. 46, 477–479 (1966)

    Google Scholar 

  7. Glasenapp, I. v., Leonhardi, G.: Über den Cholesterinstoffwechsel in der gesunden und der psoriatisch veränderten Haut. Arch. Dermatol. Syph. (Berl.) 196, 148–154 (1953)

    Google Scholar 

  8. Green, R. S., Downing, D. T., Pochi, P. E., Strauss, J. S.: Anatomical variations in the amount and composition of human skin surface lipids. J. Invest. Dermatol. 54, 240–247 (1970)

    Google Scholar 

  9. Greither, A.: Psoriasis: Eine Allgemeinkrankheit? Hautarzt 28, 5–9 (1977)

    Google Scholar 

  10. Grütz, O. Das Psoriasis-Problem im Lichte ätiologischer Forschungen und klinisch-diätetischer Erfahrungen. Arch. Dermatol. Syph. (Berl.) 170, 143–153 (1934)

    Google Scholar 

  11. Haahti, E., Horning, E. C.: Isolation and characterisation of saturated and unsaturated fatty acids and alcohols of human skin surface lipids. Scand J. Clin. Lab. Invest. 15, 73–76 (1963)

    Google Scholar 

  12. Herrmann, F., Ippen, H., Schäfer, H., Stüttgen, G.: Biochemie der Haut. Stuttgart: G. Thieme 1973

    Google Scholar 

  13. Herrmann, F., Scher, R. Coon, W. M., Mandol, L.: The acid number of the lipids on the intact and stripped surface in psoriatics. J. Invest. Dermatol. 35, 47–56 (1960)

    Google Scholar 

  14. Herrmann, F., Scher, R., Coon, W. M., Mandol, L.: Untersuchungen der Lipoide in verschiedenen Bezirken der Hautoberfläche und in verschiedenen Lagen der Hornschicht (Menge, Säurezahl und Ausbreitungsindex). Hautarzt 11, 8–15 (1960)

    Google Scholar 

  15. Kellum, R. E.: Human sebaceous gland lipids. Analysis by thin layer chromatography. Arch. Dermatol. 95, 218–220 (1967)

    Google Scholar 

  16. Konopik, J., Zaruba, F., Belsan, I., Zvereva, E., Spangalova, I.: Zur Diagnose der latenten Psoriasis. Arch. Klin. Exp. Dermatol. 227, 841–844 (1966)

    Google Scholar 

  17. Mackenna, R. B. M., Wheatley, V. R., Wormall, A.: The fatty acid composition of the surface skin fats (“sebum”) in acne vulgaris and in seborrhoic dermatitis. J. Invest. Dermatol. 33, 57–64 (1959)

    Google Scholar 

  18. Marchionini, A., Manz, E., Huß, F.: Der Cholesteringehalt der Hautoberschicht bei der Seborrhoe und bei der Psoriasis. Arch. Dermatol. Syph. (Berl.) 176, 613–645 (1938)

    Google Scholar 

  19. Neumann, E., Kuta, A.: Role of skin adnexes in pathogenesis of psoriasis. Dermatologica 116, 400–408 (1958)

    Google Scholar 

  20. Nicolaides, N., Foster, R.: Esters inhuman hair fat. J. Am. Oil Chem. Soc. 33, 404–408 (1956)

    Google Scholar 

  21. Nicolaides, N., Rothmann, S.: Studies on the chemical composition of human hair fat. I. The squalen cholesterol relationship in children and adults. J. Invest. Dermatol. 19, 389–391 (1952)

    Google Scholar 

  22. Nicolaides, N., Rothmann, S.: Studies on the chemical composition of human hair fat. II. The overall composition in regard to age, sex and race. J. Invest. Dermatol. 21, 9–14 (1953)

    Google Scholar 

  23. Peter, G., Schröpl, F., Lippross, R., Weiss, G.: Gaschromatographische Untersuchungen der Talgdrüsenlipide. I. Bestimmung der Gesamtlipide. Arch. Klin. Exp. Dermatol. 239, 12–21 (1970)

    Google Scholar 

  24. Reinertson, R. P., Wheatley, V. R.: Studies on the chemical composition of human epidermal lipids. J. Invest. Dermatol. 32, 49–59 (1959)

    Google Scholar 

  25. Rothmann, S.: Abnormalities in the chemical composition of the skin surface film in psoriasis. Arch. Dermatol. Syph. (Chic.) 62, 814–819 (1950)

    Google Scholar 

  26. Strauss, J. S., Pochi, P. E.: The quantitative gravimetric determination of sebum production. J. Invest. Dermatol. 36, 293–298 (1961)

    Google Scholar 

  27. Swanbeck, G., Thyresson, N.: A study of the state of aggregation of the lipids in normal and psoriatic horny layers. Acta Dermatol.-Venereol. (Stockh.) 42, 445–457 (1962)

    Google Scholar 

  28. Weber, C.: Psoriasis vulgaris Handbuch der Haut- und Geschlechtskrankheiten, 10. Aufl. Bode, H. G., Korting, G. W. (Hrsg.). Stuttgart: G. Fischer 1970

    Google Scholar 

  29. Unna, P. G.: Biochemie der Haut. Jena: G. Fischer 1913

    Google Scholar 

  30. Unna, P. G., Godoletz, L.: Die Hautfette. Biochem. Z. 20, 469–478 (1909)

    Google Scholar 

  31. Wheatley, V. R.: The lipid components of the psoriatic skin. Proc. XII Int. Congr. Dermatol. Washington 1962

  32. Wheatley, V. R., Farber, E. M.: Studies on the chemical composition of psoriatic scales. J. Invest. Dermatol. 36, 199–211 (1961)

    Google Scholar 

  33. Windhorst, D. B., Foster, R. C.: Studies in cholesterol and cholesterolesters in skin surface fats. J. Invest. Dermatol. 29, 339–346 (1957)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Stodtmeister, W., Nissen, H.P., Schirren, C. et al. Fettsäureverteilung der Haarlipide bei der Psoriasis vulgaris. Arch Dermatol Res 264, 339–343 (1979). https://doi.org/10.1007/BF00412662

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00412662

Key words

Schlüsselwörter

Navigation