Summary
The effects of all-trans retinoic acid on human epidermal cell cultures were studied using ultrastructural techniques. Differentiation and stratification were reduced in retinoic acid treated epidermal cells. Treated cells developed a rounded appearance and seemed to contain more granules and vacuoles than usual. Desmosomes were not found in treated cells.
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Konohana, I., Hashimoto, T., Dykes, P.J. et al. Effects of all-trans retinoic acid on the morphology of human epidermal cells in vitro. Arch Dermatol Res 279, 459–464 (1987). https://doi.org/10.1007/BF00412592
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DOI: https://doi.org/10.1007/BF00412592