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An investigation of drug induced sensory disturbances

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Summary

Previous investigations have suggested that, at least in part, the psychological disturbances which are produced by administration of phencyclidine are attributable to sensory changes. In particular it is suggested that the symptoms produced by the drug might be a result of a partial sensory deprivation.

The results obtained on 12 experimental and 6 control subjects tend to support this contention, as the drug appears to produce general impairment insensitivity in various modalities. It was also noted that the sensory changes tended to occur well in advance of psychological disturbance, a finding consistent with the theory advanced in this paper.

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Authors and Affiliations

  1. Institute of Psychiatry, Maudsley Hospital, London S.E.5

    F. S. Morgenstern, H. R. Beech & B. M. Davies

Authors
  1. F. S. Morgenstern
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  2. H. R. Beech
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  3. B. M. Davies
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Additional information

Working under a grant from the National Institutes of Health of America, no. MY-2612 (C 2) PMY (5).

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Morgenstern, F.S., Beech, H.R. & Davies, B.M. An investigation of drug induced sensory disturbances. Psychopharmacologia 3, 193–201 (1962). https://doi.org/10.1007/BF00412105

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  • DOI: https://doi.org/10.1007/BF00412105

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