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Durchlässigkeit der isolierten Rinderlinsenkapsel für Aminosäuren und wasserlösliche Eiweiße

Permeability of the isolated lens capsule to amino acids and water-soluble proteins

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Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Aims and scope Submit manuscript

Summary

A mixture of 18 amino-acids was investigated. Results showed that the isolated lens capsule is completely permeable for these molecules. It seems possible that by the negative potential of the capsule the permeation for basic amino-acids is encouraged, since their ratio in the amount of permeated amino-acids is increased.

Among a mixture of water-soluble lens proteins only the fraction of the γ-crystallin is able to penetrate the capsule, while for α- and β-crystallin the capsule proves impermeable.

Zusammenfassung

An einem Gemisch von 18 verschiedenen Aminosäuren wird gezeigt, daß die isolierte Rinderlinsenkapsel für diese Moleküle frei durchlässig ist. Möglicherweise wird durch die negative Ladung der Kapsel der Durchtritt basischer Aminosäuren begünstigt, da ihr Anteil im Kapseldurchlauf erhöht ist.

Aus einem Gemisch wasserlöslicher Linseneiweißkörper vermag die Fraktion des γ-Kristallins die Kapsel zu passieren, α- und γ-Kristallin treten nicht durch.

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Literatur

  • François, J., Rabaey, M.: Permeability of the capsule for lens proteins. Acta ophthal. (Kbh.) 36, 837–844 (1958)

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  • Friedenwald, J. S.: Permeability of the lens capsule. Arch. Ophthal. 3, 182–193 (1930)

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Authors and Affiliations

  1. Abteilung Biochemie des Auges im Institut für experimentelle Ophthalmologie der Universität Bonn, Deutschland

    Otto Hockwin, Nariosang Poonawalla, Else Noll & Werner Licht

  2. Universitäts-Augenklinik Bonn, Deutschland

    Otto Hockwin, Nariosang Poonawalla, Else Noll & Werner Licht

Authors
  1. Otto Hockwin
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  2. Nariosang Poonawalla
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  3. Else Noll
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  4. Werner Licht
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Hockwin, O., Poonawalla, N., Noll, E. et al. Durchlässigkeit der isolierten Rinderlinsenkapsel für Aminosäuren und wasserlösliche Eiweiße. Albrecht von Graefes Arch. Klin. Ophthalmol. 188, 175–181 (1973). https://doi.org/10.1007/BF00410970

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  • DOI: https://doi.org/10.1007/BF00410970

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