Abstract
Addition of amethopterin to medium before inoculation inhibited DNA synthesis and induced microcycle sporogenesis in Bacillus brevis spp. AG4. Synthesis of RNA and proteins occurred at a considerably reduced rate.
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Abbreviations
- TVC:
-
total viable counts
- HSC:
-
heat stable counts
- CDGS:
-
chemically defined medium for growth and sporulation
- TCA:
-
trichloro acetic acid
References
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Pandey, N.K., Gollakota, K.G. Induction of microcycle sporulation in Bacillus brevis spp. AG4 by amethopterin. Arch. Microbiol. 114, 189–191 (1977). https://doi.org/10.1007/BF00410783
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DOI: https://doi.org/10.1007/BF00410783