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Die Wirkung der Cholesterin-Dauerfütterung auf den Lipoidgehalt der Cornea von Kaninchen

Effect of long-term cholesterol feeding on the lipoid content of the cornea of rabbits

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Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Aims and scope Submit manuscript

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Summary

The effect of three months of cholesterol feeding on the lipoid composition of the corneas of rabbits was examined by quantitative, chromatographical and histological methods. As a partial symptom of generalised atherosclerosis the lipids also increases in the corneas generally. As a significant change the appearance of cholesterol ester could also be demonstrated.

Zusammenfassung

Die Verfasser haben den Einfluß einer dreimonatigen Cholesterinfütterung auf die Zusammensetzung der Lipoide in der Cornea mit quantitativen, chromatographischen und histologischen Methoden verfolgt. Als Teilerscheinung einer Atherosklerose waren die Lipoide allgemeinhin auch in der Cornea vermehrt. Als wesentliche Veränderung war auch das Erscheinen von Cholesterinestern nachweisbar.

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Literatur

  • Andrews, J. S.: The lipids of arcus senilis. Arch. Ophthal. 68, 264–266 (1962).

    Google Scholar 

  • Berg, N. O.: A histological study of masked lipids. Acta path. microbiol. scand., Suppl. 90, 1–192 (1951).

    Google Scholar 

  • Constantinides, P.: Experimental atherosclerosis. Amsterdam: Elsevier Co. 1965.

    Google Scholar 

  • D'Asaro, B. S., R. G. Young, and H. H. Williams: Biochemistry of the eye. III. Lipids of the lens, cornea, iris, ciliary body, and retina. Arch. Ophthal. 51, 596–598 (1954).

    Google Scholar 

  • Denden, A., u. O. W. Thiele: Über die funktionelle Bedeutung der Lipide in der Cornea. Albrecht v. Graefes Arch. Klin. exp. Ophthal. 173, 339–350 (1967).

    Google Scholar 

  • Folch, J., M. Lees, and G. H. Sloane Stanley: A simple method for the isolation and purification of total lipides from animal tissues. J. biol. Chem. 226, 297–509 (1957).

    Google Scholar 

  • Kahán, A., K. László I.: Dünnschichtchromatographische Untersuchung der Lipoide der Erythrocyten und des Serums. Kisérl. Orvostud. 19, 342–349 (1967).

    Google Scholar 

  • Krause, A. C.: The lipids of the sclera, cornea, choroid and iris. Amer. J. Physiol. 110, 182–186 (1934).

    Google Scholar 

  • Sachs, B. A., and L. Wolfman: Thin layer chromatography of blood lipids. Proc. Soc. exp. Biol. (N.Y.) 115, 1138–1141 (1964).

    Google Scholar 

  • Stahl, E.: Dünnschicht-Chromatographie, S. 497–515. Berlin-Göttingen-Heidelberg: Springer 1962.

    Google Scholar 

  • Zak, B., R. C. Dickenman, E. G. White, H. Burnett, and P. Cherney: Rapid estimation of free and total cholesterol. Amer. J. clin. Path. 24, 1307–1325 (1954).

    Google Scholar 

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Authors and Affiliations

  1. Universitäts-Augenklinik Szeged, Ungarn

    Z. Vass, I. Tapasztó & J. Polgár

Authors
  1. Z. Vass
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  2. I. Tapasztó
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  3. J. Polgár
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Vass, Z., Tapasztó, I. & Polgár, J. Die Wirkung der Cholesterin-Dauerfütterung auf den Lipoidgehalt der Cornea von Kaninchen. Albrecht von Graefes Arch. Klin. Ophthalmol. 178, 306–312 (1969). https://doi.org/10.1007/BF00410476

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  • DOI: https://doi.org/10.1007/BF00410476

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