Abstract
Clinical observation of corneal grafts often reveals subepithelial whitish opacities or membranes. To further understand this phenomenon, we undertook a histopathologic study of the changes in this region in failed human corneal grafts. Thinning and thickening of the epithelium, breaks in Bowman's membrane, and growth of subepithelial fibrous tissue were observed. Close association was found between the subepithelial fibrous growth, the breaks in Bowman's membrane, and stromal inflammation.
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Dr. Lahav in on leave at Eye Research Institute of Retina Foundation, Boston, Massachusetts
This work was supported by grants from the Swiss Fund for Research in Ophthalmology and from Herbert Lotman of Philadelphia, Pennsylvania
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Lahav, M., Cadet, JC. Subepithelial fibrous tissue in failed corneal grafts. Albrecht von Graefes Arch. Klin. Ophthalmol. 211, 145–154 (1979). https://doi.org/10.1007/BF00410138
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DOI: https://doi.org/10.1007/BF00410138